Severe Manifestations of Sickle Cell Anemia in a White American Child

Noronha PA , Honig GR Sickle cell anemia in two white American children: Essential laboratory criteria for diagnosis. Pediatrics 1979;63:242-6.

Campbell JJ , Oski FA Sickle cell anemia in an American white boy of Greek ancestry. Am J Dis Child 1977; 131:186-8.

Daland GA , Castle WB A simple and rapid method for demonstrating sickling of the red blood cells: the use of reducing agents. J Lab Clin Med 1948;33:1082.

Betke K. , Marti HR , Schlicht I. Estimation of small percentages of foetal hemoglobin. Nature 1959;184:1877-8.

Herrick JB Peculiar elongated and sickle-shaped red blood corpuscles in a case of severe anemia. Arch Intern Med 1910;6:517-21.

Cooley TB , Lee P. Sickle cell anemia in a Greek family. Am J Dis Child 1929;38:103-6.

Gelpi AP , Perrine RP Sickle cell disease and trait in white populations. J Am Med Ass 1973;224:605-8.

Gelpi AP Migrant populations and the diffusion of the sickle-cell gene. Ann Int Med 1973;79:258-64.

Perrine RP , Pembrey ME , Perrine JP , et al. Natural history of sickle cell anemia in Saudi Arabia. Ann Int Med 1978;88:1-6.

Aksoy M. Sickle cell anemia in south Turkey. A study of 15 cases in 12 white families . Blood 1956;11:460-72.

Haghshenass M. , Ismail-Beigi F. , Clegg JB , et al. Mild sickle cell anemia in Iran associated with high levels of fetal hemoglobin. J Med Gen 1977;14:168-71.

Ali SA Milder variant of sickle cell disease in Arabs in Kuwait associated with unusually high levels of fetal hemoglobin. Brit J Hem 1970;19:613-19.

Serjeant GR , Richards R. , Barbon PR , et al. Relatively benign sickle cell anemia in 60 patients aged over 30 in the West Indies. Brit Med J 1968;3:86-91.

Steinberg MH , Dreiling B. , Morrison FS , et al. Mild sickle cell disease—clinical and laboratory studies. J Am Med Ass 1973; 224:317-21.

Powars DR , Weiss JN , Chan LS , et al. Is there a threshold level of fetal hemoglobin that ameliorates morbidity in sickle cell anemia? Blood 1984 ;63:921-6.

Charache S. , Dover G. , Smith K. , et al. Treatment of sickle cell anemia with 5-azacytidine results in increased fetal hemoglobin production and is associated with non random hypomethylation of DNA around the gamma-delta-beta globin gene complex. Proc Natl Acad Sci USA 1983;80:4842-6.

Nagel RL The origin of the hemoglobin S gene: Clinical, genetic and anthropological consequences. Einstein Quarterly J of Biol and Med 1984;2:53-62.

Nagel RL , Fahey ME , Pagnier J. , et al. Hematologically and genetically distinct forms of sickle cell anemia in Africa. N Engl J Med 1985;312:880-4.

Rucknagel DL Paper electrophoretic survey of hemoglobins of American Indians. J Lab Clin Med 1957;49:896-9.

Pollitzer WS , Chernoff AL , Horton LL , et al. Hemoglobin patterns in American Indians . Science 1959;129:216.

McGrew CW Sickle cell trait in the white population. J Am Med Ass 1973;224:1762.

Farber MD , Koshy M. , Kinney TR Comparative study of sickle cell disease: Demographic and socioeconomic characteristics of patients and families with sickle cell disease. J Chron Dis 1985;38:495-505.

Schneider RG , Haggard ME , Gustavson LP , et al. Genetic hemoglobin abnormalities in about 9,000 black and 7,000 white newborns. BR J Haematol 1974;28:515-24.