Hypersensitivity Pneumonitis Due to Dove Antigens in an Adolescent

Abstract

Hypersensitivity pneumonitis is infrequently reported in children. This article describes a 15-year-old girl who presented with insidious onset of dyspnea and weight loss. A hamster and doves were housed in her bedroom. Chest radiographs showed bilateral nodular infiltrates. Pulmonary function tests showed a restrictive pattern with O₂ desaturation at rest. The diagnosis was substantiated by the presence of precipitating antibody to dove serum and droppings and by clinical improvement, along with marked improvement in pulmonary function test, after the doves were removed from her environment. The importance of making an early diagnosis to prevent debilitating fibrotic lung disease is emphasized. A detailed environmental history is essential.

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References

Hargreave FE , Pepys J. Allergic respiratory reactions in bird fanciers provoked by allergen inhalation provocation tests: relation to clinical features and allergic mechanisms. Allergy Clin Immunol 1972;50:157-73.

Reed CE , Sosman A. , Barbee RA Pigeon-breeders' lung: a newly observed interstitial pulmonary disease. JAMA 1965;193:261-5.

Stiehm ER , Reed CE , Tooley WH Pigeon breeder's lung in children. Pediatrics 1967;39:904-15.

Purtilo DT , Brem J. , Ceccaci L. , et al. A family study of pigeon breeders' disease. J Pediatr 1975;86:569-71.

Cunningham AS , Fink JN , Schlueter DP Childhood hypersensitivity pneumonitis due to dove antigens. Pediatrics 1976;58:436-42.

Fink JN , Sosman AJ Allergic lung diseases not mediated by IgE. Med Clin North Am January 1974;58:157-63.

Hargreave FE , Pepys J. , Longbottom JL , et al. Bird breeder's (fancier's) lung. Lancet 1966;1:445-9.

Levy MB , Fink JN Hypersensitivity pneumonitis. Ann Allergy 1985;54:167-72.

Chandra S. , Jones HE Pigeon fancier's lung in children. Arch Dis Child 1972;47:716-8.

10.

Van den Bosch Jmm , Heye C. , Wagenaar SS , et al. Bronchoalveolar lavage in extrinsic allergic alveolitis. Respiration 1986;49:45-51.