An infant with isoimmune thrombocytopenia and presumed intrauterine intra cranial hemorrhage is presented. This infant developed focal seizures on day 6 of life which were controlled with phenobarbital. Presently, the infant is growing and developing normally. Previous cases have been described and are summarized in this paper. There is no known method for predicting or preventing this particular complication.
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References
1.
Morris MBThrombocytopenic purpura in the newborn. Arch Dis Child1954;29:75.
McIntosh S., O'Brien RT, Schwartz AD, et al. Neonatal isoimmune purpura: response to platelet infusions. J Pediatrics1973;82:1020.
4.
Pearson HA, Shulman NR, Marder VJ, et al. Isoimmune thrombocytopenic purpura—Clinical and therapeutic consideration. Blood1964;23:154.
5.
Murray JM, Harris REThe management of the pregnant patient with idiopathic thrombocytopenic purpura . Am J Obstet Gynecol1976; 126:449.
6.
Sitarz AL, Driscoll JM, Wolff JAManagement of isoimmune neonatal thrombocytopenia. Am J Obstet Gynecol1976;124:39.
7.
Shulman NR, Marder VJ, Hillar MC, et al. Platelet and leucocyte antigens and their antibodies: serologic, physiologic, and clinical studies. Prog Hematol1964;4:222.
8.
Zalneraitis EL, Young Tsk, Krishamoorthy KSIntracranial hemorrhage in utero as a complication of isoimmune thrombocytopenia. J Pediatr1979;95: 611.
9.
Naidu S., Messmore H., Caserta V., et al. CNS lesions in neonatal isoimmune thrombocytopenia. Arch Neurol1983;40:552.
10.
Tedeschi CG, Eckert WG, Tedeschi LGForensic medicine: a study in trauma and environmental hazards. Philadelphia: WB Saunders, 1977:46.
11.
Strassman G.Hemosiderin and tissue iron in the brain, its relationship, occurrence and importance: a study of 93 human brains. J Neuropathol Exp Neurol1945;4:393.
12.
Paichak AF, Aster RH, Opitz JMEffect of maternal-fetal platelet incompatibility on fetal development. Pediatrics1984;74:570.