Persistent pulmonary hypertension of the neonate (PPHN) characteristically is seen in full-term or postterm infants. Occasionally, PPHN complicates the course of hyaline membrane disease in preterm infants. This report documents the unusual occurrence of PPHN in a preterm very low birthweight infant without apparent pulmonary parenchymal disease.
Get full access to this article
View all access options for this article.
References
1.
Drummond WHPersistent pulmonary hypertension of the neonate (persistent fetal circulation syndrome). In: Barness LA, ed. Advances in pediatrics. Vol. 30. Chicago: Year Book Medical Publishers, 1983.
2.
Drummond WH, Peckham GJFox WWThe clinical profile of the newborn within persistent pulmonary hypertension: observations in 19 affected neonates. Clin Pediatr1977;16:335.
3.
Fox WW, Duara S.Persistent pulmonary hypertension in the neonate: diagnosis and management . J Pediatr1983;103:505.
4.
Gersony WM, Duc GUSinclair JC"PFC" syndrome (persistence of the fetal circulation). Circulation1969;39[Suppl III]:87.
5.
Drummond WH, Gregory GA, Heymann MA, et al. The independent effects of hyperventilation, tolazoline and dopamine on infants with persistent pulmonary hypertension. J Pediatr1981;98:603.
6.
Goetzman BW, Sunshine P., Johnson JD et al. Neonatal hypoxia and pulmonary vasospasm: response to tolazoline . J Pediatr1976;89:617.
7.
Stevenson DK , Kasting DS, Darnall RA, Jr., et al. Refractory hypoxemia associated with neonatal pulmonary disease: the use and limitations of tolazoline. Pediatr1979;95:595.
8.
Hatle L., Angetsen B.Doppler ultrasound in cardiology. Philadelphia : Lea and Febiger, 1983:72.
9.
Burstin L.Determination of pressure in the pulmonary artery by external graphic recordings . Br Heart J1967;29:396.
10.
Stevenson JGKawabori I., Guntheroth WGNon-invasive estimation of peak pulmonary artery pressure by M-mode echocardiography. J Am Coll Cardiol1984;4:1021.
11.
Swischuk LE , Richardson CJ, Nichols MM, et al. Primary pulmonary hypoplasia in the neonate. J Pediatr1979;95:573.
12.
Nimrod C., Varela-Gittings F., Machin G., et al. The effect of very prolonged membrane rupture on fetal development . Am J Obstet Gynecol1984; 148: 540.
13.
Worthington D., Maloney Aha, Smith BTFetal lung maturity. I. Mode of onset of premature labor. Obstet Gynecol1977;49:275.
14.
Bucciarelli RL, Nelson RM, Egan EA, et al. Transient tricuspid insufficiency of the newborn: a form of myocardial dysfunction in stressed newborns. Pediatrics1977;59:330.
15.
Levin DL, Heyman MA, Kitterman JA, et al. Persistent pulmonary hypertension of the newborn infant. J Pediatr1976;89:626.
16.
Levin DL, Stanger P., Kitterman JA, et al. Congenital heart disease in low birth weight infants. Circulation1975;52:500.
17.
Valdez-Cruz LM, Dudell GGFerrara A.Utility of M-mode echocardiography for early detection of infants with persistent pulmonary hypertension of the newborn . Pediatrics1981;68:515.
18.
Tyler T., Leffler C., Wallis R., et al. Effects of prostaglandins of the E series on pulmonary and systemic circulations of newborn goats during normoxia and hypoxia. Prostaglandins1975; 10:963.
19.
Lock J., Olley P., Coceni F.Direct pulmonary vascular responses to prostaglandins in the conscious newborn lamb. Am J Physiol1980;238:H631.
20.
Cassin S., Tod M., Philips J., et al. Effects of prostaglandin D2 on perinatal circulation . Am J Physiol1981;240: H755.