A new routine infant formula has been developed and clinically tested. The clinical study reported here involved 337 normal newborns cared for by six private pediatric group practices. Infants were examined regularly by the investigators until six months of age. Serum biochemistries, hematology, and growth and tolerance variables were compared to infants fed control formulas and to reported values for breast-fed infants. This new formulation compared favorably, in all areas studied here, to controls and previously reported values.
Get full access to this article
View all access options for this article.
References
1.
Gaull G., Sturman JA, Raiha Ncr.Development of mammalian sulfur metabolism: absence of cystathionase in human fetal tissues. Pediatr Res1972;6:538-47.
2.
Raiha Ncr, Heinonen K., Rassin DK, et al. Milk protein quantity and quality in low-birthweight infants: I. Metabolic responses and effect on growth. Pediatrics1976;57:659-74.
3.
Rassin DK, Gaull GE, Heinonen K., et al. Milk protein quantity and quality in low-birthweight infants: II. Effects on selected aliphatic amino acids in plasma and urine. Pediatrics1977;59:407-22.
4.
Gaull GE, Rassin DK, Raiha Ncr, et al. Milk protein quantity and quality in low-birth weight infants. III. Effects on sulfur amino acids in plasma and urine. J Pediatr1977;90:348-55.
5.
Rassin DK, Gaull GE, Raiha Ncr, et al. Milk protein quantity and quality in low-birth weight infants. IV. Effects on tyrosine and phenylatanine in plasma and urine. J Pediatr1977;90:3;356-360.
6.
Gaull GE, et al. Human milk as food. In: Milunsky A, Friedman E, and Gluck L, eds. Advances in perinatal medicine . Vol. 2. New York: Plenum, 1982.
7.
Cordano A., Gastunaduy A., Graham GGEvaluation of protein quality and fat digestibility of a new whey-based infant formula. (submitted for publication)
8.
Fomon SJ, Thomas LN, Filer LJ, et al. Food consumption and growth of normal infants fed milk-based formulas. Acta Paediatr Scand1971;223(Suppl):1-36.
9.
Ahn CH, MacLean WC. Growth of the exclusively breast-fed infant. Am J Clin Nutr1980;33:183-92.
10.
Fomon SJ, Filer LJ, Thomas LN, et al. Growth and serum chemical values of normal breastfed infants . Acta Paediatr Scand1970;202(Suppl):
Stewart A., Westropp C.Breast-feeding in the Oxford Child Health Survey. Part II: Comparison of bottle- and breastfed babies. Br Med J1953;2:305-8.
13.
Mellander O. , Valquist B., Melibin T., et al. Breast-feeding and artificial feeding: a clinical, serological, and biochemical study in 402 infants with a survey of the literature. Acta Paediatr Scand1959 ;48(Suppl): 116.
14.
Jacobs A., Path Frc, Worwood M.Ferritin in serum clinical and biochemical implications. N Engl J Med1975; 292:951-6.
15.
Thomas WJ, Koenig HM, Lightsey AL, et al. Free erythrocyte porphyrin:hemoglobin ratios, serum ferritin and transferrin saturation levels during treatment of infants with iron deficiency anemia. Blood1977;49:455-62.
16.
Piomelli S. , Brickman A., Caroles E.Rapid diagnosis of iron deficiency by measurement of free erythrocyte porphyrins and hemoglobin: the FEP:hemoglobin ratio. Pediatrics1976; 57:1.
17.
PediatricClinical Chemistry. A survey of normals, methods, and instrumentation, with commentary. Washington, DC: American Association for Clinical Chemistry, 1977:20, 123, 185.
18.
Oski FAIron-fortified formulas and gastrointestinal symptoms in infants: a controlled study. Pediatrics1980;66:168-70.
