A retrospective chart analysis of patients referred to the Allergy Service was undertaken to determine which historical and laboratory data most closely correlated with the presence of atopy. The serum IgE level was highly significant for all patients when analyzed as a group (p < 0.0001). Other factors assumed significance when the patients were analyzed by individual age groups. Guidelines for the logical assessment of the child suspect of atopy are proposed.
Get full access to this article
View all access options for this article.
References
1.
Spitz E., Gelfant EW, Sheffer AL, et al. Serum IgE in clinical immunology and allergy. J Allergy Clin Immunol1972;49:337-47.
2.
Orgel A., Kemp JP, Meltzer EO, et al. Atopy and IgE in a pediatric allergy practice. Ann Allergy1977;39:161-8.
3.
Brown WG, Halonen MJ, Kaltenborn WT, et al. The relationship of respiratory allergy, skin test reactivity and serum IgE in a community population sample. J Allergy Clin Immunol1979;63:328-35.
4.
Kjellman N-IM.Predictive value of high IgE levels in children . Acta Pediatr Scand1976;65:465-71.
5.
Kjellman N-IM , Johansson Sgo, Roth A.Serum IgE levels in healthy children quantified by a sandwich technique (PRIST). Clin Allergy1976;6:51-9.
6.
Church JA, Richards W.Routine laboratory determinations in pediatric allergic disease. Ann Allergy1978;41:137.
7.
Walker SH, Duncan DBEstimation of the probability of an event as a function of several independent variables. Biometrika1967;54:167-9.
8.
Berg T., Johansson SGIgE concentration in children with atopic Int, ArchAllergy1969:36:219-32.
9.
Yunginger JW , Gleich GJThe impact of the discovery of IgE on the practice of allergy. Pediatr Clin North Am1972;22:3-150.
10.
Orgel HA, Hamburger RN, Bazaral M., et al. Development of IgE and allergy in infancy. J Allergy Clin Immunol1975;56:296-307.
11.
Wittig JH, Gerrard JWAge of onset of asthma and allergic rhinitis in relation to gamma-E globulin (IgE). J Clin Esophagootorhinolaryngol Allerg1979;41:40-5.
