Combined Fetal Alcohol and Hydantoin Syndromes

Abstract

Two infants, born with extensive abnormalities probably resulting from maternal use of alcohol and hydantoin during pregnancy, are described. The findings suggest the speculation that con current exposure to these teratogens, in utero, may have synergistic or additive effects upon a fetus, producing serious malformations. The purpose of this report is to alert physicians to this combined syndrome. Its occurrence may be more common than anticipated.

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