Our experience with a microtechnique using 99mTc-DTPA for determination of glomerular filtration rate in 172 children is presented. It is a simple finger-stick method carried out in a four-hour time period by trained nuclear medical per sonnel. The procedure meets all criteria for precise measurement of glomerular filtration rate, and the radiation dose is low. Proof of accuracy was obtained by comparison of this technique with concomitant 24-hour urinary creatinine clear ance in a subset of children.
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References
1.
Versage PM, Patton DD, Brill AB, et al: Measurement of glomerular filtration rate (GFR). Recent Advances in Nuclear Medicine. Atlanta, Southeastern Chapter, Society of NuclearMedicine, 1975, p 1-6
2.
Braren V., Versage PM, Touya JJ, et al: Radioisotopic determination of glomerular filtration rate. J Urol121:145, 1979
3.
Bauer JD, Toro G., Ackerman PG: Creatinine determination Bray's Clinical Laboratory Methods. St Louis, CV Mosby Co, 1962, p 65
4.
Hauser W., Atkins HL, Nelson KG, et al: Technetium— 99mTc-DTPA: a new radiopharmaceutical for brain and kidney scanning. Radiology94:679, 1970
