This report documents a case of hypertension caused by an intrarenal arterial stenosis in a ten-year-old girl. The renovascular origin of her hypertension was suggested by a positive saralasin acetate infusion test, and the lesion was identified by use of the subtraction technique in renal arteriography. Partial nephrectomy resulted in resolution of the pa tient's hypertension with good function in the remaining portion of the kidney.
Get full access to this article
View all access options for this article.
References
1.
Korobkin M., Perloff DL, Palubinskas AJ: Renal arteriography in the evaluation of unexplained hypertension in children and adolescents. J Pediatr88:388, 1976
2.
Clayman AS, Bookstein JJ: The role of renal arteriography in pediatric hypertension. Radiology108: 107, 1973
3.
Leumann EP, et al: Renovascular hypertension in children. Pediatrics46:362, 1970
4.
Lambeth CB, Derrick JR, Hansen AE: Stenosis of a branch of the renal artery causing hypertension in a child. Including a complication of translumbar renal arteriography. Pediatrics26:822, 1960
5.
Smith JP, Saylor ML: Renal vascular hypertension in children. J Urol84:17, 1960
6.
Niall JF, Murphy L.: Segmental renal artery stenosis with hypertension in childhood: Med J Aust2:372, 1965
7.
Schambelan M. : Selective renin-vein renin sampling in hypertensive patients with segmental renal lesions. N Eng J Med290:1153, 1974
8.
Bourgorgnie J., et al: Renal venous renin in hypertension . Am J Med48:332, 1970
9.
Tucker RM, et al: Renovascular hypertension. Relationship of surgical curability to renin-angiotensin activity. Mayo Clin Proc53:373, 1978
10.
Eyler WR, et al: Angiography of the renal areas including a comparative study of renal artery stenosis in patients with and without hypertension. Radiology74:879, 1962
11.
Brunner HR, Gavras H., Laragh J.H.: Angiotensin-II blockade in man by Sar-1-Ala-8-angiotensin II for understanding and treatment of high blood pressure. Lancet2: 1045, 1973
12.
Streeten Dhp , et al: Use of an angiotensin II antagonist (saralasin) in the recognition of "angiotensinogenic" hypertension. N Engl J Med292:657, 1975
13.
Marks LS: Saralasin bolus test. Rapid screening procedure for renin-medicated hypertension . Lancet2:784, 1975
14.
Case DB, et al: Usefulness and limitations of saralasin, a partial competitive agonist of angiotensin II, for evaluating the renin and sodium factors in hypertensive patients. Am J Med60:825, 1976
15.
Streeten Dhp , Anderson GH, Dalakos TG: Angiotensin blockade: its clinical significance . Am J Med60:817, 1976
16.
Wilson, HM, et al: Saralasin infusion in the recognition of renovascular hypertension . Ann Intern Med87:36, 1977
17.
Colman RW, et al: The human plasma kallikrein kinin system. Prog Hematol7:255, 1971
18.
Marks LS, Maxwell MH, Kaufman JJ: Renin, sodium, and vasodepressor response to saralasin in renovascular hypertension . Ann Intern Med87:176, 1977
19.
Maxwell MH: Cooperative study of renovascular hypertension: current status. Kidney Int8:S153, 1975
20.
Maxwell MH, Marks LS: Angiotensin blockade by saralasin bolus injection. Kidney Int15:S53, 1979
21.
Horne ML, et al: Angiotensin II profiling with saralasin: summary of Eaton collaborative study. Kidney Int15:S115, 1979
22.
Trainin EB, et al: Negative saralasin response in correctable renovascular hypertension . J Pediatr93:460, 1978
23.
Favre L., et al: Angiotensin II blockage by saralasin in the evaluation of hypertension in children. Kidney Int15:S75, 1979
24.
Bookstein JJ : Radiologic aspects of renovascular hypertension. Part 1. Aims and methods of radiology study group. JAMA220:1218, 1972