The Beckwith-Wiedemann Syndrome

Beckwith, J.B. : Extreme cytomegaly of the adrenal fetal cortex, omphalocele, hyperplasia of kidneys and pancreas and Leydig-cell hyperplasia —another syndrome? Presented at the Annual Meeting of Western Society for Pediatric Research, Los Angeles, California, Nov. 11, 1963.

Beckwith, J.B. , Wang, C. , Donnell, G.N. , and Gwinn, J.L. : Hyperplastic fetal visceromegaly with macroglossia, omphalocele, cytomegaly of the adrenal fetal cortex, postnatal somatic gigantism, and other abnormalities: a newly recognized syndrome. Abstract read at Annual Meeting of American Pediatric Society, Seattle, Washington , June 16-18, 1964.

Filippi, G. , and McKusick, V.A. : The Beckwith-Wiedemann syndrome; report of two cases and review of literature . Medicine 49: 279, 1970.

Bronstein, I.P. , Abelson, S.M. , Jeffee, R.H. , and Von Bonen , G. : Macroglossia in children; review of literature, report of case of true muscular hypertrophy and suggested classification. Am. J. Dis. Child. 54: 1328, 1937 .

Koop, C.E. , and Moschakis, E.A. : Capillary lymphangioma of the tongue complicated by glossitis. Pediatrics 27: 800, 1961.

Shafer, A.D. : Primary macroglossia. Clin. Pediatr. 7: 357, 1968.

Arous, M.S. , Solitare, G.B. , and Grunt, J.A. : The macroglossia of Beckwith's syndrome. Plast. Reconstr. Surg. 45: 341, 1970.

Sherman, F.E. , Bass, L.E. , and Fetterman , G.H. : Congenital metastasizing adrenal cortical carcinoma associated with cytomegaly of the fetal adrenal cortex. Am. J. Clin. Pathol. 30: 439, 1958.

Neeman, J. , cited by Beckwith, J.B. : Macroglossia, omphalocele, adrenal cytomegaly, gigantism and hyperplastic visceromegaly. In Bergsma, D. (Ed.): Birth Defects. Original Article Series 5: 188, 1969.

Wilson, F.C. , and Orlin, H. : Crossed congenital hemihypertrophy associated with Wilm's tumor. J. Bone Joint Surg. 47: 1609, 1965 .

Tower, J. , and Beck, P.C. , cited by Beckwith, J.B. : Macroglossia, omphalocele, adrenal cytomegaly, gigantism and hyperplastic visceromegaly. In Bergsma, D. (Ed.): Birth Defects. Original Article Series 5: 188, 1969.

Beckwith, J.B. : Macroglossia, omphalocele, adrenal cytomegaly, gigantism and hyperplastic visceromegaly. Proceedings of the First Conference on the Clinical Delineation of Birth Defects, Baltimore, Maryland, May 20-25, 1968.

Cohen, M.M. , Gorlin, R.J. , Feingold, M. , and Bensel, R.W. : The Beckwith-Wiedemann syndrome. Am. J. Dis. Child. 122: 515, 1971.

Sotelo-Avila, C. , and Singer, D.B. : Syndrome of hyperplastic fetal visceromegaly and neonatal hypoglycemia (Beckwith's Syndrome). Pediatrics 46: 240, 1970.

Gellis, S.S. , and Hsia, D.Y.Y. : The infant of the diabetic mother. Am. J. Dis. Child. 97: 1, 1959.

Irving, I. : Exomphalos with macroglossia: a study of 11 cases. J Pediatr. Surg. 2: 499, 1967.

Ruffie, J. , Virenque, J. , Bardier, R. , and Colombies, P. : Remaniements chromosomiques complexes portant sur les autosomes s'accompaqnant d' anomalies craniofaciales et d'un omphalocele. C. R. Acad. Sci. (Series D) 262: 386, 1966.

Wiedemann, H.R. : Complexe malformatif familial avec hernie ombilicale et macroglossie. Un "syndrome nouveau"? J. Genet. Hum. 13: 223, 1964.

Mariani, R. , Unal, D. , Spriet, A. , Carcassonne, M. , and Bernard, R. : Hypoglycemie du nouveau-ne' avec microcephalie macroglossie et megalosplechnie. Arch. Franc. Pediatr. 26: 337, 1969.