Review of the literature and experience with 19 CNS infections in infants with CNS malformations suggest prognosis is not worse with neonates with mal formations and is directly related to virulence of the infecting organism. Re covery is also dependent on treatment that will provide bacteriocidal levels of antibiotic into the infected tissue and fluids and on correction of disturbed in tracranial fluid dynamics, both tissue fluid (edema) and cerebrospinal fluid.
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