Chlorphentermine proves to be a suc cessful anorexigenic agent in this study. When compared to a placebo, it produced a significant degree of weight loss and maintained its value for up to nine months of follow up. It has replaced all other drugs for the treatment of obese adoles cents in this busy clinic.
Get full access to this article
View all access options for this article.
References
1.
Anand, B.K. and Brobeck, J.R.: Hypothalamic control of food intake in rats and cats. Yale J. Biol. Med.24: 123, 1951.
2.
Emele, J.F., Shanaman, J. and Warren, M.R.: Chlorphentermine hydrochloride, a new anorexigenic agent. Fed. Proc.20: 328 (Part I), 1961.
3.
Fineberg, S.K. : Evaluation of anorexigenic agents; studies with chlorphentermine. Amer. J. Clin. Nutr.11: 509, 1962.
4.
Gallagher, J.Roswell: Medical Care of Adolescents, 2nd Ed. New York, Appleton Century Crofts, 1966.
5.
Gruelich, W.W. et al.: Somatic and endocrine studies of pubertal and adolescent boys. Monogr. Soc. Res. Child Develop. 7: National Research Council, Washington, D. C., 1942.
6.
Heald, F.P. and Hunt, S.M.: Caloric dependency in obese adolescents as affected by degree of maturation . J. Pediat.66: 1035, 1965.
7.
Lorber, J.: Obesity in childhood. Arch. Dis. Child.41: 309, 1966.
8.
Mayer, J.: Some aspects of the problem of regulation of food intake and obesity . New Eng. J. Med.274: 610, 1966.
9.
Morgane, P.J. : Distinct "feeding" and "hunger motivating" systems in the lateral hypothalamus of the rat. Science133: 887, 1961.
10.
Spargo, J.A. , Heald, F.P. and Peckos, P.S.: Adolescent obesity. Nutrition Today1-4: 2, 1966.
