Abstract
Get full access to this article
View all access options for this article.
References
1.
Friedman
MJ
Sharieff
GQ
. Seizures in children . Pediatr Clin North Am . 2006 ;53 :257 -277 .
2.
Nieh
SE
Sherr
EH
. Epileptic encephalopathies: new genes and new pathways . Neurotherapeutics . 2014 ;11 :796 -806 .
3.
Nakamura
K
Kato
M
Osaka
H
. Clinical spectrum of SCN2A mutations expanding to Ohtahara syndrome . Neurology . 2013 ;81 :992 -998 .
4.
DeVries
SP
Patel
AD
. Two patients with a GRIN2A mutation and childhood-onset epilepsy . Pediatr Neurol . 2013 ;49 :482 -485 .
5.
Kim
JB
. Channelopathies . Korean J Pediatr . 2014 ;57 :1 -18 .
6.
Catterall
WA
. Sodium channels, inherited epilepsy, and antiepileptic drugs . Annu Rev Pharmacol Toxicol . 2014 ;54 :317 -338 .
7.
Gazina
EV
Leaw
BT
Richards
KL
. ‘Neonatal’ Nav1.2 reduces neuronal excitability and affects seizure susceptibility and behaviour . Hum Mol Genet . 2015 ;24 :1457 -1468 .
8.
Yamakawa
K
. Na channel gene mutations in epilepsy—the functional consequences . Epilepsy Res . 2006 ;70 (suppl 1 ):S218 -S222 .
9.
Ragsdale
DS
. How do mutant Nav1.1 sodium channels cause epilepsy? Brain Res Rev . 2008 ;58 :149 -159 .
10.
Burnashev
N
Szepetowski
P
. NMDA receptor subunit mutations in neurodevelopmental disorders . Curr Opin Pharmacol . 2015 ;20 :73 -82 .
11.
Pavone
P
Spalice
A
Polizzi
A
Parisi
P
Ruggieri
M
. Ohtahara syndrome with emphasis on recent genetic discovery . Brain Dev . 2012 ;34 :459 -468 .
12.
Lado
FA
Rubboli
G
Capovilla
G
Avanzini
G
Moshe
SL
. Pathophysiology of epileptic encephalopathies . Epilepsia . 2013 ;54 (suppl 8 ):6 -13 .
13.
Vigevano
F
Arzimanoglou
A
Plouin
P
Specchio
N
. Therapeutic approach to epileptic encephalopathies . Epilepsia . 2013 ;54 (suppl 8 ):45 -50 .
14.
Malik
SI
Galliani
CA
Hernandez
AW
Donahue
DJ
. Epilepsy surgery for early infantile epileptic encephalopathy (Ohtahara syndrome) . J Child Neurol . 2013 ;28 :1607 -1617 .
15.
McTague
A
Cross
JH
. Treatment of epileptic encephalopathies . CNS Drugs . 2013 ;27 :175 -184 .
16.
Farooque
P
Detyniecki
K
Mattson
RH
. Epilepsy ; Antiepileptic drug profiles . In:
Aminoff
MJ
Daroff
RB
, eds. Encyclopedia of the Neurological Sciences Vol. 2 . 2nd ed. San Diego, CA : Academic Press ; 2014 :81 -92 .