Detection of P53 Gene Mutations in its Full Translational Sequence by Cleavase Fragment Length Polymorphism Analysis

Bergh J Norberg T Sjogren S Lindgren A Holmberg L . Complete sequencing of the p53 gene provides prognostic information in breast cancer patients, particularly in relation to adjuvant systemic therapy and radiotherapy. Nat Med 1995; 1: 1029–34.

Aas T Borresen AL Geisler S Smith-Sorensen B Johnsen H Varhaug JE Specific P53 mutations are associated with de novo resistance to doxorubicin in breast cancer patients. Nat Med 1996; 2: 811–4.

Sheffield VC Beck JS Kwitek AE Sandstrom DW Stone EM . The sensitivity of single-strand conformation polymorphism analysis for the detection of single base substitutions. Genomics 1993; 16: 325–32.

Condie A Eeles R Borresen AL Coles C Cooper C Prosser J . Detection of point mutations in the p53 gene: comparison of single-strand conformation polymorphism, constant denaturant gel electrophoresis, and hydroxylamine and osmium tetroxide techniques. Hum Mutat 1993; 2: 58–66.

Lyamichev V Brow MAD Dahlberg JE . Structure-specific endonucleolytic cleavage of nucleic acids by eubacterial DNA polymerases. Science 1993; 260: 778–83.

Hsu IC Tokiwa T Bennett W Metcalf RA Welsh JA Sun T p53 gene mutation and integrated hepatitis B viral DNA sequences in human liver cancer cell lines. Carcinogenesis 1993; 14: 987–92.