An Investigation of Hyperandrogenism and Obesity Presenting during Late Childhood

Robinson S Kiddy D Gelding SV Willis D Niththyananthan Bush A . The relationship of insulin sensitivity to menstrual pattern in women with hyperandrogenism and polycystic ovaries. Clin Endocrinol 1993; 39: 351–5

Nestler JE Strauss JF . Insulin as an effector of human ovarian and adrenal steroid metabolism. Endocr Metab Clinics N Am 1991; 20: 807–24

Nestler JE . Sex hormone-binding globulin: A marker for hyperinsulinaemia and/or insulin resistance [Editorial]. J Clin Endocrinol Metab 1993; 76: 273–4

Ameil SA Caprio S Sherwin RS Plewe G Haymond MW Tamborlane WV . Insulin resistance of puberty: A defect of peripheral glucose metabolism. J Clin Endocrinol Metab 1991; 72: 277–82

Richards GE Cavallo A Meyer WJ Prince MJ Peters EJ Stuart CA . Obesity, acanthosis nigricans, insulin resistance, and hyperandrogenemia: Pediatric perspective and natural history. J Pediat 1995; 107: 893–7

National Institute of Health Lipid Research Clinics Program Manual of Laboratory Operations; No. (NIH) 75–628. Washington, DC: DHEW Publications, 1975

Shackleton CHL . Mass spectrometry in the diagnosis of steroid-related disorders and in hypertension research. J Steroid Biochem Molec Biol 1993; 45: 127–40

Warwick GL Packard CJ Steward JP Watson TDG Burns L Boulton-Jones JM . Postprandial lipoprotein metabolism in nephrotic syndrome. Eur J Clin Invest 1992; 22: 813–20

Barbieri RL Ryan KJ . Hyperandrogenism, insulin resistance, and acanthosis nigricans: A common endocrinopathy with distinct pathophysiologic features. Am J Obstet Gynaecol 1983; 147: 90–101

Kahn CR Flier JS Bar RS Archer JA Gorden P Martin MM . The syndromes of insulin resistance and acanthosis nigricans. N Eng J Med 1976; 294: 739–45

Stewart PM Shackleton CHL Beastall GH Edwards CRW . 5α-reductasc activity in PCOS. Lancet 1990; 335: 431–3

Wallace AM Buchanan LM Thomson JA . Reduction of free androgen index associated with decreased 5α-reductase activity during treatment for hirsutism [Abstract]. Proc Ninth Internal Cong Endocrinol 1992; 486 (P-14.04.044)

Rodin A Thakkar H Taylor N Clayton R . Hyperandrogenism in the polycystic ovary syndrome. N Eng J Med 1994; 330: 460–5

Conway GS Agrawal R Betteridge DJ Jacobs HS . Risk factors for coronary artery disease in lean and obese women with polycystic ovary syndrome. Clin Endocrinol 1992; 37: 119–25

Robinson S Henderson AD Gelding SV Kiddy D Niththyananthan R Bush A . Dyslipidaemia is associated with insulin resistance in women with polycystic ovaries. Clin Endocrinol 1996; 44: 277–84

Caro JF . Insulin resistance in obese and non-obese man. J Clin Endrocrinol Metab 1991; 73: 691–5

Nikkila EA . Familial lipoprotein lipase and related disorders of chylomicron metabolism. In: Stanbury JB Wyngaarden JB Frederikson DS Goldstein JL Brown MS , eds. The Metabolic Basis of Inherited Disease, 54th edn. New York: McGraw Hill, 1983: 622–42

Brunzell JD Porte D Bierman EL . Abnormal lipoprotein-lipase-mediated plasma triglyceride removal in untreated diabetes mellitus associated with hypertriglyceridemia. Metabolism 1979; 28: 901–7