Hirsuitism: Free and Bound Testosterone

Blight LF Judd SJ White GH . Relative diagnostic value of serum non-SHBG-bound testosterone, free androgen index and free testosterone in the assessment of mild to moderate hirsuitism. Ann Clin Biochem 1989; 26: 311–16.

Tait JF Burstein S. In vivo studies of steroid dynamics in man. In: Pincus V Thimann KV Astwood EB , eds. The Hormones. vol. V. New York: Academic Press, 1964; 441–557.

Ekins RP . The free hormone concept. In: Hennemann G , ed. Thyroid Hormone Metabolism. New York: Marcel Dekker, 1985; 77–106.

Pardridge WM . Transport of protein-bound hormones into tissues in vivo. Endocr Rev 1981; 2: 102–23.

Pardridge WM . Transport of protein-bound thyroid and steroid hormones into tissues in vivo: a new hypothesis on the role of hormone binding plasma proteins. In: Albertini A Ekins RP , eds. Free Hormones in Blood. Amsterdam: Elsevier/North Holland, 1982; 45–52.

Ekins RP Edwards PR Newman B. The role of binding proteins in hormone delivery. In Albertini A Ekins R , eds. Free Hormones in Blood. Amsterdam: Elsevier/North Holland, 1982; 3–43.

Pardridge WM Landaw EM . Tracer kinetic model of blood-brain barrier transport of plasma protein-bound ligands. Empiric testing of the free hormone hypothesis. J Clin Invest 1984; 74: 745–52.

Ekins RP . Measurement of free hormones in blood. Endocr Rev (in press).

Mendel CM Cavalieri RR Weisiger RA . On plasma protein-mediated transport of steroid and thyroid hormones (and reply). Am J Physiol 1988; 254 (Endocrinol Metab 17): E221–E227.

Ekins RP Edwards PR . Plasma protein-mediated transport of steroid and thyroid hormones: A critique. In: Rairia F Bradlow HL Gaidano G , Eds. Steroid Protein Interactions: Basic and Clinical Aspects (Second International Symposium on Binding Proteins). Ann N Y Acad Sci 1988; 538: 193–203.

Tait JF . The biological availability of free and protein bound steroid. In: Albertini A Ekins R , eds. Free Hormones in Blood. Amsterdam: Elsevier/North Holland, 1982; 65–70.

Chaudhuri G Steingold KA Pardridge WM Judd HL , TeBg- and CBG-bound steroid hormones in rabbits are available for influx into uterus in vivo. Am J Physiol 1988; 254 (Suppl 17): E79–E83.

Pardridge WM . Selective delivery of sex steroid hormones to tissues in vivo by albumin and by sex hormone-binding globulin. In: Rairia F Bradlow HL Gaidano G , eds. Steroid Protein Interactions: Basic and Clinical Aspects (Second International Symposium on Binding Proteins). Ann N Y Acad Sci 1988; 538: 173–92.

Ekins R. Validity of analog free thyroxin immunoassays. Clin Chem 1987; 33: 2137–52.

Midgley JEM Wilkins TA . Effect of albumin concentration on equilibrium radioimmunoassay of serum free thyroxin with labeled thyroxin analog (Amerlex Free T4). Clin Chem 1983; 29: 1861–63.

Ekins R Edwards P Jackson T Geiseler D. Interpretation of labeled-analog free hormone assay. Clin Chem 1984; 30: 491–93.

Braverman LE Chopra IJ Ekins RP Clinical significance and reliability of free thyroid hormone estimation: Panel Discussion. NucCompact 1985; 16: 399–404.

Larsen PR Alexander NM Chopra IJ Revised nomenclature for tests of thyroid hormones and thyroid-related proteins in serum. J Clin Endocrinol Metab 1987; 64: 1089–94.

Jowett T Chu T Ekins R. Validity of current analog-based free hormone immunoassays. Steroids 1988; 52: 365–66.