Growth Hormone Deficiency

Raben MS . Preparation of growth hormone from pituitaries of man and monkey. Science 1957; 125: 883–4.

Raben MS . Treatment of a pituitary dwarf with human growth hormone. J Clin Endoc Metab 1958; 18: 901–3.

Milner RG Russell-Fraser T Brook COD . Experience with human growth hormone in Great Britain: The report of the MRC working party. Clin Endocrinol 1979; 11: 15–38.

Milner RDG . Growth hormone 1985. Br Med J 1985; 291: 1593–4.

Koch TK Berg BO de Armand SJ Gravina RF . Creutzfeldt-Jakob disease in a young adult with idiopathic hypopituitarism: Possible relation to the administration of cadaveric human growth hormone. N Engl J Med 1985; 313: 731–3.

Gibbs CJ Jr Joy A Heffner R . Clinical and pathological features and laboratory confirmation of Creutzfeldt-Jakob disease in a recipient of pituitary-derived human growth hormone. N Engl J Med 1985; 313: 734–8.

Powell-Jackson J Weller RO Kennedy P . Creutzfeldt-Jakob disease after administration of human growth hormone. Lancet 1985; ii: 244–6.

Taylor DM Dickinson AG Fraser H . Preparation of growth hormone free from contamination with unconventional slow viruses. Lancet 1985; ii: 260–2.

Goeddel DV Heyneker HL Hozum T . Direct expression in Escherichia coli of a DNA sequence coding for human growth hormone. Nature 1979; 281: 544–8.

Kaplan SL Underwood LE August GP . Clinical studies with recombinant-DNA-derived methionyl human growth hormone in growth hormone deficient children. Lancet 1986; i: 697–700.

Tanner JM Whitehouse RH Hughes PCR Vince FP . Effect of human growth hormone treatment for 1 to 7 years on growth of 100 children with growth hormone deficiency, low birthweight, inherited smallness, Turner's syndrome and other complaints. Arch Dis Child 1971; 46: 745–82.

Stahnke N . Human growth hormone treatment in short children without growth hormone deficiency. N Engl J Med 1984; 310: 925–6.

Milner RDG . Which children should have growth hormone therapy? Lancet 1986; i: 483–5.

Tanner JM Hiernaux J Jarman S , Growth and physique. In: Weiner JS Louire JA , eds. Human Biology. A Guide to Field Methods. Philadelphia: F A Davis Company, 1969.

Milner RDG Burns EC . Investigation of suspected growth hormone deficiency. Arch Dis Child 1982; 57: 944–7.

Buckler JMH . How to make the most of bone ages. Arch Dis Child 1983; 58: 761–3.

Tanner JM Goldstein H Whitehouse RH . Standards for children's height at ages 2–9 years allowing for height of parents. Arch Dis Child 1970; 45: 755–62.

Tanner JM Lardt KW Cameron N . Prediction of adult height from height and bone age in childhood. Arch Dis Child 1983l 58: 767–767.

Nicoll AG Smail PJ Forsyth CC . Exercise test for growth hormone deficiency. Arch Dis Child 1984; 59: 1177–8.

De San Lazaro C Parkin JM Turner SJ . Treadmill exercise test in short children. Arch Dis Child 1984; 59: 1179–81.

King JM Price DA . Sleep-induced growth hormone release—evaluation of a simple test for clinical use. Arch Dis Child 1983; 58: 220–2.

Hindmarsh PC Smith PJ Taylor BJ . Comparison between a physiological and a pharmacological stimulus of growth hormone secretion: Response to stage IV sleep and insulin-induced hypoglycaemia. Lancet 1985; ii: 1033–5.

Gil-Ad I Topper E Laran Z . Oral clonidine as a growth hormone stimulation test. Lancet 1979; ii: 278–80.

Health Services Human Growth Hormone Committee. Comparison of the intravenous insulin and oral clonidine tolerance tests for growth hormone secretion. Arch Dis Child 1981; 56: 852–4.

Fraser NC Seth J Brown NS . Clonidine is a better test for growth hormone deficiency than insulin-induced hypoglycaemia. Arch Dis Child 1983; 58: 355–8.

Parker ML Hammond JM Daughady WH . The arginine provocation test: An aid in the diagnosis of hyposomatropism. J Clin Endocrinol Metab 1967; 29: 1129–36.

Raiti S Davis WT Blizzard RM . A comparison of the effects of insulin hypoglycaemia and arginine infusion on release of human growth hormone. Lancet 1967; ii: 1182–3.

Penny R Blizzard RM Davis WT . Sequential arginine and insulin tolerance tests on the same day. J Clin Endocrinol Metab 1969; 29: 1499–501.

Siegel SF Becker DJ Lee PA . Comparison of physiologic and pharmacologic assessment of GH secretions. Am J Dis Child 1984; 138: 540–3.

Saenger P Levine LS Wiedemann E . Growth with absent growth hormone by radioimmunoassay. J Pediatr 1974; 85: 137–8.

Rudman D Kutner MH Blackston RD . Children with normal-variant short stature: Treatment with human growth hormone for six months. N Engl J Med 1981; 305: 123–31.

Van Vliet G Styne DM Kaplan SL Grumbach MM . Growth hormone treatment for short stature. N Engl J Med 1983; 309: 1016–22.

Gertner JM Genel M Gianfredi RN . Prospective clinical trial of human growth hormone in short children without growth hormone deficiency. J Pediatr 1984; 104: 172–6.

Romshe CA Zipf WB Miser A . Evaluation of growth hormone release and human growth hormone treatment in children with cranial irradiation-associated short stature. J Pediair 1984; 104: 177–81.

Spiliotis BE August GP Hung W . Growth hormone neurosecretory dysfunction: A treatable cause of short stature. J Am Med Assoc 1984; 251: 2223–30.

Rudman D Kentner MH Chawla RK . The short child with subnormal plasma somatomedin C. Pediair Res 1985; 19: 975–80.

Frazer T Gavin JR Daughady WH . Growth hormone-dependent growth failure. J Pediatr 1982; 101: 12–5.

Geffner ME Lippe BM Barsch N . Growth without growth hormone: Evidence for a potent circulating human growth factor. Lancet 1986; ii: 343–6.

Teale JD Marks V . The measurement of insulin-like growth factor I: Clinical applications and significance. Ann Clin Biochem 1986; 23: 413–24.

Kowarski AA Thompson RG Migeon CJ . Determination of integrated concentration of true secretion rate of human growth hormone. J Clin Endocrinol Metab 1971; 32: 356–60.

Zadik Z Chalew SA Raiti S Kowarski AA . Do short children secrete insufficient growth hormone? Pediatrics 1985; 76: 355–60.

Grossman A Savage MO Blacklay A . Use of growth hormone releasing hormone in the diagnosis and treatment of short stature. Horm Res 1985; 21: 52–7.

Rona RJ Tanner JM . Aetiology of idiopathic growth hormone deficiency in England and Wales. Arch Dis Child 1977; 52: 197–208.

Blatt J Baren BB Gillin C . Reduced pulsatile growth hormone secretion in children after therapy for acute lymphoblastic leukaemia. J Pediatr 1984; 104: 182–6.

Kendall B . Current approaches to hypothalamic–pituitary radiology. Clin Endocrinol Metab 1983; 12: 535–66.

Parkin JM . Incidence of growth hormone deficiency. Arch Dis Child 1974; 49: 904–5.

Vimpani GV Vimpani AF Lidgard GP . Prevalence of severe growth hormone deficiency. Br Med J 1977; 2: 427–30.

Prcece MA Tanner JM Whitehouse RH Cameron N . Dose dependence of growth response to hGH in “isolated” growth hormone deficiency. J Clin Endocrinol Metab 1976; 42: 477–83.

Wilson DM Baker B Hintz RL Rosenfeld RG . Subcutaneous versus intramuscular growth hormone therapy: Growth and acute somatomedin response. Pediatrics 1985; 76: 361–4.

Albertsson-Wikland K Westphal O Westgren U . Daily subcutaneous administration of human growth hormone in growth hormone deficient children. Acta Paediatr Stand 1986; 75: 89–97.

Data Sheet ‘Somatonorm 4IU’ Kabivitrum/574 1/86.

Repaske DR Phillips JA . Molecular analysis of familial growth hormone disorders. Bioessays 1986; 4: 114–8.

Swift J. Gulliver's Travels. London, 1726.