The Laboratory Investigation of Paraproteinaemia

Kohn J. Benign paraproteinaemias. J Clin Path 1975; 28 (Suppl. 6): 77–82.

Heremans JF Masson P L . Specific analysis of immunoglobulins. Techniques and clinical value. Clin Chem 1973; 19: 294–300.

Hobbs J R . Immunocytoma o' mice an' men. Brit Med J 1971; ii: 67–72.

Hobbs J R . Growth rates and responses to treatment in human myelomatosis. Brit J Haematol 1969; 16: 607–17.

Cuzick J Cooper EH MacLennan ICM The prognostic value of serum B2 microglobulin compared with other presentation features in myelomatosis. Br J Cancer 1985; 52: 1–6.

Moya FJ Miller S L . Characterisation of paraproteins with and without the aid of Immunoelectrophoresis. Clin Chem 1985; 31: 23A.

Peto R. Urea, albumin and response rates. Brit Med J 1971; 2: 324.

Hobbs J R . Paraproteins. Proc Roy Soc Med 1969; 62: 773–779.

Kohn J. Cellulose acetate electrophoresis and immunoelectrophoresis. In ( Smith I , ed.), Chromatographic and Electrophoretic Techniques Vol. 2. London: Heineman, 1976; 90–137.

Jeppson JO Laurell CB Franzen B . Agarose gel electrophoresis. Clin Chem 1979; 25: 629–38.

Gore ME Riches PG Kohn J . Identification of the paraproteins and clinical significance of more than one paraprotein in the serum of 56 patients. J Clin Pathol 1979; 32: 313–7.

Whicher JT Warren C Chambers R E . Immunochemical assays for immunoglobulins. Ann Clin Biochem 1984; 21: 78–91.

Ritchie RF Smith R Immunofixation I. II Application to the study of monoclonal proteins. Clin Chem 1976; 22: 1982–5.

Grabar P Williams C A . Methode permettant I'etude conjugee des proprietes electrophoretiques et immunochimiques d'un melange de proteines. Application au serum sanguin. Biochim Biophys Acta 1953; 10: 193–4.

Merlini G Piro P Pavesi F . Detection and identification of monoclonal components: Immunoelectrophoresis on agarose get and immunofixation on cellulose acetate compared. Clin Chem 1981; 27: 1862–5.

Whicher J T . Immunofixation on cellulose acetate is more efficient than immunoelectrophoresis for detection of paraproteins. Clin Chem 1983; 29: 402–3.

Kohn J Riches P G . A cellulose acetate immunofixation technique. J Immunol Methods 1978; 20: 325–31.

Schultz AL Fink LM Iliff M . Immunofixation of cryoglobulins. Pitfalls and solutions. Clin Chem 1985; 31: 791–2.

Whicher J T . Problems encountered in immunochemical technique. Methdology. In: ( Ward A Milford Whicher JT , eds), Immunochemistry in Clinical Laboratory Medicine. Lancaster, UK: MTP Press, 1979; 51–61.

Smith AM Thompson R A . Paraprotein estimation: a comparison of immunochemical and densitometric techniques. J Clin Path 1978; 31: 1156–60.

Medical Research Council. Prognostic factors in the third MRC myelomatosis trial. Br J Cancer 1980; 42: 831–40.

Bataille R Grenier J Sany J . Bcta-2-microglobulin in myeloma: optimal use for staging, prognosis and treatment—a prospective study of 160 patients. Blood 1984; 63: 468–76.

Playford RJ Dawnay A Cattell WR Landon J . The development of a fluoroimmunoassay for β-2-microglobulin in scrum. Ann Clin Biochem 1985; 22: 166–170.

Bernier GM Putnam F W . Polymcrism, polymorphism and impurities in Bence Jones proteins. Biochem Biophys Acta 1964; 86: 295–308.

Bradshaw T R . The recognition of myelopathic albumin in urine. Brit Med J 1906; ii: 1442–4.

Hobbs J R . Bence Jones proteins. Essays Med Biochem 1975; 1: 105–31.

Whicher JT Hawkins L Higginson J . Clinical applications of immunofixation: a more sensitive technique for the detection of Bence Jones protein. J Clin Pathol 1980; 33: 779–80.

Gale DSJ Versey JMB Hobbs J R . Rocket immunoselection for the detection of heavy chain disease. Clin Chem 1974; 20: 1292–4.

Carter PM Hobbs J R . Clinical significance of 7S IgM in monoclonal IgM diseases. Brit Med J 1971; ii: 260–1.