Computer Models for Metabolic Studies on Plasma Proteins

Bohme A. Uber die Schwankungen der Serumkonzentration beim gesunden Menschen. Dt Arch Klin Med 1911; 103: 522–62.

Atkins GL . Multicompartment Models for Biological Systems. London: Methuen, 1969.

Shipley RA Clark RF . Tracer Methods for In-vivo Kinetics. London: Academic Press, 1972.

Matthews CME . The theory of tracer experiments with ¹³¹I-labelled plasma proteins. Phys Med Biol 1957; 2: 36–53.

Gibaldi M Perrier D. Pharmacokinetics. New York: Marcel Delck, 1975.

Sterling K. The turnover rate of serum albumin in man as measured by ¹³¹I-tagged albumin. J Clin Invest 1951; 30: 1228–37.

McFarlane AS . Metabolism of plasma proteins. In: Munro HN Allison JB , eds. Mammalian Protein Metabolism, Vol. 1. New York: Academic Press, 1964; 297–341.

Rossing N. (1967) The normal metabolism of ¹³¹I-labelled albumin in man. Clin Sci 1967; 33: 593–602.

Ballantyne FC Fleck A. Experience with a commercial preparation of ¹²⁵I-labelled human albumin for study of albumin metabolism. J Clin Pathol 1973; 26: 499–502.

Rossing N Barenholdt O. Whole-body counting in metabolic studies of ¹³¹I-labelled albumin. Scand J Clin Lab Invest 1967; 19: 331–8.

Fleck A. In preparation.

Andersen SB . Metabolism of Human Gamma Globulin. Oxford: Blackwell Scientific Publications, 1964.

Takeda Y Reeve EB . Distribution and excretion of ¹³¹I-iodide in men on pharmacologic doses of iodides. J Lab Clin Med 1962; 60: 944–53.

Campbell RM Cuthbertson DP Matthews CM Behaviour of ¹⁴C and ¹³¹I-labelled plasma proteins in the rat. Int I Appl Radial Isot 1956; 1: 56–84.

Nosslin B. Analysis of disappearance time-curves after single injection of labelled proteins. In: Wolstenholme GEW O'Connor M , eds. Protein Turnover, Ciba Foundation Symposia 9. London: North Holland Associated Scientific Publishers, 1973.

Wraight EP . The place of deconvolution analysis in plasma protein turnover studies. Phys Med Biol 1969; 14: 463–70.

Bianchi R Mariane G Pilo A Short term determination of plasma protein turnover by a two-tracer technique using plasma only or plasma and urine data. In: Wolstenholme GEW O'Connor M , eds. Protein Turnover. Ciba Foundation Symposia 9 (new series). London: North Holland Associated Scientific Publishers, 1973.

McFarlane AS . Measurement of synthesis rates of liver-produced plasma proteins. Biochem J 1963; 89: 277–90.

Rossing N Parving HH Lassen NA . Albumin transcapillary escape rate as an approach to microvascular physiology in health and disease. In: Bianchi R Mariani G MacFarlane AS , eds. Plasma Protein Turnover. London: MacMillan, 1976.

Tavill AS Craigie A Rosenoer VM . The measurement of the synthetic rate of albumin in man. Clin Sci 1968; 34: 1–28.

Wochner RD Weissman SM Waldmann TA Direct measurement of the rates of synthesis of plasma proteins in control subjects and patients with gastrointestinal protein loss. J Clin Invest 1968; 47: 971–82.

Keys A Brozek J Henschel A The Biology of Human Starvation, Vols I and II. Minneapolis: The University of Minnesota Press, 1950.

Fleck A Munro HN . Protein metabolism after injury. Metabolism 1963; 12: 783–9.

Grossman J Yalow AA Weston RE . Albumin degradation and synthesis as influenced by hydrocortisone, corticotrophin and infection. Metabolism 1960; 9: 528–50.

Dykes PW Davies JWL Ricketts CR The effect of plasma concentration on the catabolic rate of human serum albumin. In: Donato L Milhand C Sirchis J , eds. Labelled Proteins in Tracer Studies. Brussels: Euratom, 1966; 113–21.

Andersen SB Rossing N. Metabolism of albumin and G-globulin in man during albumin infusions and during plasmapheresis. In: Birke G Norberg R Plantin LO , eds. Physiology and Pathophysiology of Plasma Protein Metabolism. Oxford: Pergamon Press, 1969; 135.

Rossing N Krastilnikoff PA Christiansen C. Plasma protein catabolism in the capillary wall? In: Peeters H , ed. Protides of the Biological Fluids, Vol. 19. Oxford: Pergamon Press, 1972; 437–41.

Skillman JJ Awwad HK Moore FD . Plasma protein kinetics of the early transcapillary refill after haemorrhage in man. Surg Gynecol Obstet 1967; 125: 983–96.

Conn HO . The use, misuse and abuse of albumin infusions. In: Rosenoer VM Oratz M Rothschild MA , eds. Albumin Structure, Function and Uses. Oxford: Pergamon Press, 1977; 1–5.

Broom J Fleck A Davidson DF Biochemical adaptations in early starvation: Observations on sex difference. Proc Nutr Soc 1978; 37: 91A.

Hoffenberg R Black E Brock JF . Albumin and globulin tracer studies in protein depletion studies. J Clin Invest 1966; 45: 143–52.

Fleck A. Injury and plasma proteins. In: Wilkinson AW Cuthbertson D , eds. Metabolism and the Response to Injury. Tunbridge Wells: Pitman Medical Publishing. 1976; 229–36.

Jarnum S Lassen NA . Albumin and transferrin metabolism in infections and toxic diseases. Scand J Clin Lab Invest 1961; 13: 357–68.

Davies JWL Ricketts CR Bull JP . Studies of plasma protein metabolism part 1. Albumin in burned and injured patients. Clin Sci 1962; 23: 411–23.

Wochner RD Weissman SM Waldmann TA Direct measurement of the rates of synthesis of plasma proteins in control subjects and patients with gastrointestinal protein loss. J Clin Invest 1968; 47: 971–82.

Ballantyne FC . Studies on albumin metabolism in injury and disease. Ph.D. Thesis, University of Glasgow, 1971.

Chow BF . The electrophoretic studies on the effect of protein depletion on plasma proteins and the regeneration of plasma proteins after oral administration of hydroylsates prepared from casein and lactalbumin. Ann NY Acad Sci 1946; 47: 297–316.

Ballantyne FC Fleck A Dick WC . Albumin metabolism in rheumatoid arthritis. Ann Rheum Dis 1971; 30: 265–70.

Dykes PW . The rates of distribution and catabolism of albumin in normal subjects and in patients with cirrhosis of the liver. Clin Sci 1968; 34: 161–83.

Ballantyne FC Fleck A. The effect of environmental temperature (20° and 30°) after injury on the catabolism of albumin in man. Clin Chim Acta 1973; 46: 139–46.

Waldmann TA Trier J Fallon H. Albumin metabolism in patients with lymphoma. J Clin Invest 1963; 42: 171–8.

Fleck A Clark B. Plasma protein concentration after injury—a simple computer model. Adv Physiol Sci 1980; 26: 81–9.

Rothschild MA Oratz M Zimraon D Albumin synthesis in cirrhotic subjects with ascites studied with carbonate-C¹⁴ . J Clin Invest 1969; 48: 344–50.

Tavill AS . Protein metabolism and the liver. In: Wright R Alberti KGMM Karran S Millward-Sadler GH , eds. Liver and Biliary Disease. London: W.B. Saunders, 1979; 83–107.

Arturson G Jonsson C-E. Transcapillary transport after thermal injury. Scand J Plast Reconstr Surg 1979; 13: 29–38.

Parving HH Rasmussen SM . Transcapillary escape rate of albumin and plasma volume in short and long-term juvenile diabetics. Scand J Clin Lab Invest 1973; 32: 81–7.

Rescigno A. A contribution to the theory of tracer methods. Biochim Biophys Acta 1956; 21: 111–6.

Churchill RV . Operational Mathematics. New York: McGraw-Hill, 1972.

Stephenson JL . Theory of transport in linear biological systems. 1. Fundamental integral equation. Bull Math Biophys 1960; 22: 1–17.

Cuénod M Durling A. A Discrete Time Approach for Systems Analysis. New York: Academic Press. 1969.