The conditions for the automated assay of plasma antithrombin activity over the clinically relevant range of 25–250% using the chromogenic substrate S2238 and the Gilford 3800 enzyme rate analyser are reported.
References
1.
KauffmannRHVeltkampJ JVan TilburgNHVan EsLA. Acquired antithrombin III deficiency and thrombosis in the nephrotic syndrome. Am J Med1978; 65: 607–10.
2.
MackieMBennettBOgstonDDouglasAS. Familial thrombosis: Inherited deficiency of antithrombin III. Br Med J1978; 1: 136–8.
3.
BarrowcliffeTWJohnsonEAThomasD.Antithrombin III and heparin. Br Med Bull1978; 34: 143–150.
4.
StamatakisJDLawrenceDKakkarW.Surgery, venous thrombosis and anti-Xa. Br J Surg1977; 64: 709–11.
5.
SagarSStamatakisJDThomasDKakkarW.Oral contraceptives, antithrombin III activity and postoperative thrombosis. Lancet1976; 1: 509–11.
