Three drift correction methods are described. The results obtained from computer simulation of these methods and their application to raw data obtained from a survey of multichannel continuous-flow analysers are discussed, with particular reference to the effects of each method on analytical precision and accuracy, and on between-analyser variation. A geometrically derived method of drift correction was found to be the most satisfactory.
References
1.
BennetA.GartelmannD.MasonJ. I.OwenJ. A. (1970). Calibration, calibration drift, and specimen interaction in Auto-Analyzer systems. Clinica Chimica Acta, 29, 161–180.
2.
FleckA.RobinsonR.BrownS. S.HobbsJ. R. (1974). Definitions of some words and terms used in automated analysis. Annals of Clinical Biochemistry Technical Bulletin, 33, 11, 242–257.
3.
GroveP. B. (Ed.) (1966). Webster's Third New International Dictionary of the English Language.G. Bill and Sons, London.
4.
HornD. B.SteinS. M.DickieR. J. (1974). The effect of temperature variation on the accuracy of results in a continuous flow analysis system. Clinica Chimica Acta, 54, 205–213.
5.
McLellandA. S.FleckA.BurnsR. F. (1978). A limited protocol for assessment of within batch performance of multichannel analysers. Annals of Clinical Biochemistry, 15, 12–17.
6.
SnedecorG. W. (1956). Statistical Methods, 5th edition. Iowa State University Press, Iowa.
7.
WhitbyL. G.SimpsonD. (1969). Experience with on-line computing in clinical chemistry. Journal of Clinical Pathology, 22, Supplement, 107–124.
