A method is described for the automation of the T3-uptake test using a discrete analyser. This enables 160 samples to be analysed in two hours at a cost of only 9p a sample. By making use of a simple correction procedure for differences in charcoal contact time and for radioactive carryover it is possible to get a within-batch precision of 2·5% and a between-batch precision of 4·6% for values within the normal range.
References
1.
GoldieD. J. (1973). In vitro assessment of thyroid function. MD thesis, Bristol
2.
GoldieD. J.JenningsR. D.McGowanG. K. (1974). The estimation of serum thyroxine by competitive binding analysis: A modified method. Journal of Clinical Pathology, 27, 74–82
3.
HarknessR. A.CrombieJ. D.MiddletonD.HoggI. (1973). An Evaluation of the BTL Analmatic Assembly.Scottish Home and Health Department: Edinburgh
4.
HerbertV.GothliebC. W.LauK-S.GilbertP.SilverS. (1965). Adsorption of I-131 triiodothyronine (T3) from serum by charcoal as an in vitro lest of thyroid function. Journal of Laboratory and Clinical Medicine, 66, 814–821
5.
WalkerW. H. C.PennockC. A.McGowanG. K. (1970). Practical considerations in kinetics of continuous flow analysis. Clinica chimica acta, 27, 421–435