P.B.I. determinations are now being replaced in many laboratories by thyroxine determinations, but the latter have previously had the disadvantage of not being automated. The Analmatic preparation unit has been adapted for the large scale determinations of serum thyroxine using the Radiochemical Centre's Thyopac-4 kits. There is satisfactory correlation between the manual and automated techniques. Both the between-batch and within-batch precision were found to be better than that for the manual method.
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