The Manchester experience of the amino acid screening programme is described. The Scriver test is simple and allows the detection of six amino acid disorders in one test. The cost is not great and the programme does not require large initial capital outlay. The number of cases detected exceeds expectation and cannot be explained.
References
1.
KomrowerG. M.RobinsA. J.Plasma aminoacid disturbance in infancy. I: Hypermethioninaemia and transient tyrosinaemia. Arch. Dis. Childh.44 (1969) 418.
2.
ScriverC. R.DaviesE.CullenA. M.Application of a simple micromethod to the screening of plasma for a variety of aminoacidopathies. Lancet2 (1964) 230.
