A PBI and thyroxine iodine manual method (Oxford Laboratories) have been compared with a serum thyroxine method based on competitive protein-binding. The thyroxine iodine technique appeared to be more reliable and practicable than the PBI method, except that the latter has the advantage that it can be automated. The close correlation between results from the serum thyroxineiodine and thyroxine methods makes the former a useful addition to the range of tests employed in the investigation of thyroid function.
References
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BirdR.JacksonD. J.A routine method for the estimation of serum protein-bound iodine. Clin. Chem.8 (1962) 389.
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MurphyB. P.JachanC. The determination of thyroxine by competitive protein-binding analysis employing an anion-exchange resin and radio thyroxine. J. Lab. Clin. Med.66 (1965) 161.
