This study utilizes continuous wave cavity ring-down spectroscopy (CW-CRDS) at a wavelength approximately 1672 nm to detect acetone and methane in exhaled human breath. We employed a commercial distributed feedback diode laser (DFB), which delivered approximately 4 mW of power across a tuning range of 3.5 nm to measure acetone and methane concentrations in exhaled human breath. A detection limit of about 10.5 parts per billion (ppb) was demonstrated. Samples were collected from two distinct population locations, 23 individuals from Doha, Qatar, and 19 volunteers from College Station, Texas. The content of multiple gas mixture components was determined. The developed method for retroactive determination of the laser tuning eliminated the need for online wavelength determination. Simultaneous measurements of acetone and methane in exhaled breath can assist in diagnosing and monitoring diabetes and in assessing metabolic profiles of individuals using this noninvasive technique.
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