The recently described hyalinizing clear cell carcinoma of salivary tissues joins other clinicopathologic entities in its segregation from the formerly nondescript and heterogeneous classification “clear cell neoplasms.” The carcinoma is preponderantly an intraoral (palate and base of tongue) neoplasm that is always infiltrative and capable of regional lymph node metastasis. To date, it has responded to locoregional control treatments and has not been life-consuming.
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