Abstract
Desmoplastic melanoma is an uncommon type of malignant melanoma that has a predilection for the skin of the head and neck. Because of a progressive metaplasia of melanocytes and an accompanying desmoplasia, the neoplasm can be mistaken for benign or malignant soft tissue lesions. The neurotropism exhibited by many desmoplastic melanomas is a strong adverse factor for prognosis; otherwise, the biologic behavior is not unlike that of conventional melanomas.
Get full access to this article
View all access options for this article.
References
1.
Conley
J
Lattes
R
Orr
W
. Desmoplastic malignant melanoma (a rare variant of spindle cell melanoma) . Cancer 1971 ; 28 : 914 –36 .
2.
Bruijn
JA
Mihm
MC
Barnhill
RL
. Desmoplastic melanoma . Histopathology 1992 ; 20 : 197 –206 .
3.
Batsakis
JG
Bauer
R
Regezi
JA
Campbell
T
. Desmoplastic melanoma of the maxillary alveolus . J Oral Surg 1979 ; 37 : 107 –9 .
4.
Jain
S
Allen
PW
. Desmoplastic malignant melanoma and its variants. A study of 45 cases . Am J Surg Pathol 1989 ; 13 : 358 –73 .
5.
Smithers
BM
McLeod
GR
Little
JH
. Desmoplastic melanomas: Patterns of recurrence . World J Surg 1992 ; 16 : 186 –90 .
6.
Beenken
S
Byers
R
Smith
JL
Goepfert
H
Shallenberger
R
. Desmoplastic melanoma. Histologic correlation with behavior and treatment . Arch Otolaryngol Head Neck Surg 1989 ; 115 : 374 –9 .
7.
Reiman
HM
Goellner
JR
Woods
JE
Mixter
RC
. Desmoplastic melanoma of the head and neck . Cancer 1987 ; 60 : 2269 –74 .
8.
Egbert
B
Kempson
R
Sagebiel
R
. Desmoplastic malignant melanoma. A clinicopathologic study of 25 cases . Cancer 1988 ; 62 : 2033 –41 .
9.
From
L
Hanna
W
Kahn
HJ
Gruss
J
Marks
A
Baumal
R
. Origin of the desmoplasia in desmoplastic melanoma . Hum Pathol 1983 ; 14 : 1072 –80 .
