Abstract
Laryngeal angiosarcoma is uncommon, with only 19 previously reported cases. Malignant transformation in nonirradiated hemangiomas is extremely rare, with only five equivocal cases reported, all of which occurred in the skin. We report the first documented case of malignant transformation in a laryngeal hemangioma, and review the literature.
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References
1.
Morales
PH
Lindberg
RD
Barkley
HT
Jr.
. Soft tissue angiosarcomas . Int J Radiat Oncol Biol Phys 1981 ; 7 : 1655 –9 .
2.
Pratt
LW
Goodof
II
. Hemangioendotheliosarcoma of the larynx . Arch Otolaryngol 1968 ; 87 : 484 –9 .
3.
Triplet
I
Vankemmel
B
Madelain
M.
Hémangioendothéliome malin du larynx avec métastases sous-cutanées . Lille Med 1974 ; 19 : 743 –5 .
4.
Thomas
RL
. Non-epithelial tumours of the larynx . J Laryngol Otol 1979 ; 93 : 1131 –41 .
5.
Ferlito
A
Nicolai
P
Caruso
G.
, Angiosarcoma of the larynx. Case report . Ann Otol Rhinol Laryngol 1985 ; 94 : 93 –5 .
6.
Batsakis
JG
Fox
JE
. Supporting tissue neoplasms of the larynx . Surg Gynecol Obstet 1970 ; 131 : 989 –97 .
7.
Cady
B
Rippey
JH
Frazell
EL
. Non-epidermoid cancer of the larynx . Ann Surg 1968 ; 167 : 116 –20 .
8.
Krajina
Z.
Laryngeal sarcoma . Can J Otolaryngol 1975 ; 4 : 303 –6 .
9.
Stewart
FW
Treves
N.
Lymphangiosarcoma in postmastectomy lymphoedema: A report of six cases in elephantiasis chirurgia . Cancer 1948 ; 1 : 64 –81 .
10.
Jones
E Wilson
. Malignant angioendothelioma of the skin . Br J Dermatol 1964 ; 76 : 21 –39 .
11.
Rosai
J
Summer
HW
Kostianovsky
M
Perez-Mesa
C.
Angiosarcoma of the skin: A clinicopathologic and fine structural study . Hum Pathol 1976 ; 1 : 83 –109 .
12.
Girard
C
Johnson
WC
Graham
JH
. Cutaneous angiosarcoma . Cancer 1970 ; 26 : 863 –83 .
13.
Maddox
JC
Evans
HL
. Angiosarcoma of skin and soft tissue: A study of forty-four cases . Cancer 1981 ; 48 : 1907 –21 .
14.
Moseley
HF
. Interscapulothoracic amputation . In:
Pack
GT
Ariel
IM
, eds. Tumors of the soft somatic tissues and bone . 2nd ed. New York, NY : Harper and Row , 1964 : 253 –83 . (Treatment of cancer and allied diseases ; vol 8 .).
15.
Mach
K.
Zur frage des lymphangioendotheliomas: I Klinischer teil . Arch Klin Exp Dermatol 1966 ; 226 : 318 –26 .
16.
Lo
TCM
Silverman
ML
Edelstein
A.
, Postirradiation haemangiosarcoma of the chest wall. Report of a case . Acta Radiol Oncol 1985 ; 24 : 237 –40 .
17.
Narula
AA
Vallis
MP
El-Silimy
OE
Dowling
F
Bradley
PJ
. Radiation induced angiosarcomas of the nasopharynx . Eur J Surg Oncol 1986 ; 12 : 147 –52 .
18.
Otis
CN
Peschel
R
McKhann
C
Merino
MJ
Duray
PH
. The rapid onset of cutaneous angiosarcoma after radiotherapy for breast carcinoma . Cancer 1986 ; 57 : 2130 –4 .
19.
Jones
E Wilson
. Malignant vascular tumours . Clin Exp Dermatol 1976 ; 1 : 287 –312 .
20.
Bean
WB
. Dyschondroplasia and hemangiomata (Maffucci's syndrome) . Arch Intern Med 1955 ; 95 : 767 –78 .
21.
Davidson
TI
Kissin
MW
Bradish
CF
Westbury
G.
Angiosarcoma in a patient with Maffucci syndrome . Eur J Surg Oncol 1985 ; 11 : 381 –4 .
22.
Farr
HW
Carandag
CM
Huvos
AG
. Malignant vascular tumors of the head and neck . Am J Surg 1970 ; 120 : 501 –4 .
23.
Hodgkinson
DJ
Soule
EH
Woods
JE
. Cutaneous angiosarcoma of the head and neck . Cancer 1979 ; 44 : 1106 –13 .
24.
Panje
WR
Moran
WJ
Bostwick
DG
Kitt
VV
. Angiosarcoma of the head and neck: Review of 11 cases . Laryngoscope 1986 ; 96 : 1381 –4 .
