We report two cases of Hanhart's syndrome. The first patient was a male who died in the neonatal period, and whose temporal bones were removed, processed, and histologically examined; the findings are presented in this article. The second case concerns a living patient with the typical characteristics of the syndrome. An attempt is made to show that a gross first and second branchial arch anomaly exists in this syndrome and not just the micrognathia that is obvious to the onlooker. Possible causes and classifications of facial dysmorphia are discussed.
HanhartE. Über die Kombination von Peromelia mit Mikrognathie, ein neues Syndrom beim Menchen, entsprechend der Akroteriasis congenita von Wriedt und Mohr beim Rinde. Arch Julius Klaus — Stift Vererbungsforsch Sozialanthropol Rassenhyg1950; 25: 531–44
2.
GrislainJMainardRBerrangerPBreletGCadudalJLBilletJ. Aglossic-adactylic et syndrome d'Hanhardt. Pediatrie1971; 26: 353–64
3.
WriedtCHMohrOL. Amputated, a recessive lethal in cattle; with a discussion on the bearing of lethal factors on the principles of livestock breeding. J Genet1928; 20: 187
4.
MartiusGWalterS. Peromelie und mikrognathie als missbildungskombination (Handhardt's syndrome). Geburtshilfe Frauenheilkd1954; 14: 558–63
5.
NagerFRDeReynierJP. Das Gehororgan bei den angeborenen Kopfmissbildungen. Basel: S Karger, 1948
