Using the microsphere method combined with light microscopic observation of serially sectioned plastic-embedded cochleas, the distribution of microspheres trapped within the cochlea can be observed and the regional blood flow can be determined. In the guinea pig, the blood flow is greatest in the lateral wall, high in the modiolus, and low under the organ of Corti.
AngelborgCHutzcrantzEÅgerupB. The cochlear blood flow. Acta Otolaryngol (Stockh)1977; 83: 92–7.
2.
AlmABillA. The oxygen supply to the retina. II. Effects of pressure on uveal and retinal blood flow in cats. A study with labelled microspheres including flow determination in brain and some other tissue. Acta Physiol Scand1972; 84: 306–19.
3.
AxelssonAAngelborgCLarsenHC. The microsphere surface technique for evaluation of cochlea vessels and circulation. Acta Otolaryngol (Stockh)1983; 95: 297–305.
4.
AngelborgCAxelssonALarsenHC. The regional blood flow in the rabbit cochlea. Arch Otolaryngol1984; 110: 277–300.
5.
AmeeleRJ. A method for the preparation of serial thick sections of plastic embedded plant tissue. Stain Technol1976; 51: 17–24.
6.
HultcrantzEAngelborgC. Cochlear circulation studied with microspheres. ORL1978; 40: 65–76.
7.
LarsenHC. Cochlear blood flow and hearing related to changes in osmotic and hydrostatic pressure in the inner ear. Acta Universitatis Uppsaliensis: abstracts of dissertations from the faculty of medicine, 1981.