Effect of High Intensity Impulse Noise on the Vascular System of the Chinchilla Cochlea

Abstract

Changes in the vasculature of the chinchilla cochlea were quantitatively assessed 45 days after impulse noise exposure of either 155- or 160-dB peak sound pressure level. The condition of the vessels in the lateral wall and spiral lamina of each cochlea was evaluated in terms of 20 morphological parameters. Multivariate statistical analysis identified the parameters that were significantly affected by the noise exposure. Evaluation of these significant parameters indicated a net reduction in blood flow to the cochlea. All of the noise-exposed cochleas showed vascular changes when compared to controls, and the magnitude of these changes was related to the amount of hair cell loss. The vascular changes are presumed to be permanent.

Keywords

cochlear vasculature impulse noise inner and outer hair cells

Get full access to this article

View all access options for this article.

References

Hunter-Duvar

Suzuki

Mount

. Anatomical changes in the organ of Corti after acoustic stimulation. In: Hamernik

Henderson

Salvi

, eds. New perspectives on noise-induced hearing loss. New York: Raven Press, 1982: 3–22.

Liberman

Mulroy

. Acute and chronic effects of acoustic trauma: Cochlear pathology and auditory nerve pathophysiology. In: Hamernik

Henderson

Salvi

, eds. New perspectives on noise-induced hearing loss. New York: Raven Press, 1982: 105–35.

Hawkins

Jr . The role of vasoconstriction in noise-induced hearing loss. Ann Otol Rhinol Laryngol 1971; 80: 903–14.

Axelsson

Vertes

. Histological findings in cochlear vessels after noise. In: Hamernik

Henderson

Salvi

, eds. New persepectives on noise-induced hearing loss. New York: Raven Press, 1982: 49–68.

Axelsson

Vertes

. Methodological aspects for the study of cochlear blood vessels. In: Portmann

Aran

, eds. Les colloques de l'Institute de la Santé et de la Recherche Medicale. Inner ear biology XIV workshop. INSERM 1977; 68: 265–70.

Axelsson

Vertes

. Vascular histology of the guinea pig cochlea. Acta Otolaryngol (Stockh) 1978; 85: 198–212.

Vertes

Axelsson

. Methodological aspects of some inner ear vascular techniques. Acta Otolaryngol (Stockh) 1979; 88: 328–34.

Hamernik

Henderson

Coling

Slepecky

. The interaction of whole body vibration and impulse noise. J Acoust Soc Am 1980; 67: 928–34.

Cooley

Lohnes

. Discriminant analysis. In: Multivariate data analysis. New York: John Wiley and Sons, 1971: 243–61.

10.

Santi

Duvall

III . Morphological alteration of the stria vascularis after administration of the diuretic bumetanide. Acta Otolaryngol (Stockh) 1979; 88: 1–12.

11.

Rüedi

. Some animal experimental findings on the functions of the inner ear. Ann Otol Rhinol Laryngol 1951; 60: 993–1023.

12.

Kellerhals

. Pathogenesis of inner ear lesions in acute acoustic trauma. Acta Otolaryngol (Stockh) 1972; 73: 249–53.

13.

Lawrence

Gonzalez

Hawkins

Jr . Some physiological factors in noise-induced hearing loss. Am Ind Hyg Assoc J 1967; 28: 425–30.

14.

Vertes

Axelsson

Miller

Liden

. Cochlear vascular and electrophysiological effects in the guinea pig to 4 kHz pure tones of different durations and intensities. Acta Otolaryngol (Stockh) 1981; 92: 15–24.

15.

Lawrence

Yantis

. Individual differences in functional recovery and structural repair following overstimulation of the guinea pig ear. Ann Otol Rhinol Laryngol 1957; 66: 595–621.

16.

Ward

Duvall

III . Behavioral and ultrastructural correlates of acoustic trauma. Ann Otol Rhinol Laryngol 1971; 80: 881–96.

17.

Hamernik

Henderson

. Impulse noise trauma: A study of histological susceptibility. Arch Otolaryngol 1974; 99: 118–21.

18.

Bohne

. Mechanisms of noise damage in the inner ear. In: Henderson

Hamernik

Dosanjh

Mills

, eds. Effects of noise on hearing. New York: Raven Press, 1976: 41–68.