Temporal Bone Histopathology Associated with Occlusion of Vertebrobasilar Arteries

Abstract

We have presented the histological findings in the inner ear of a patient who experienced occlusion of the vertebral and basilar arteries 17 days before death. A large infarction was observed in the medulla and pons on the right side. There was severe degenerative change in the right membranous labyrinth as well as in the right cochlear and vestibular nerves, which was presumably caused by ischemia from occlusion of the right labyrinthine artery. The organ of Corti and sensory epithelia of the vestibular labyrinth showed the most advanced state of degeneration. The histopathological appearance was similar to that observed in the subacute stage following obstruction of the labyrinthine arteries in animal experiments.

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References

Kimura

Perlman

. Arterial obstruction of the labyrinth. Ann Otol Rhinol Laryngol 1958; 67: 5–40.

Perlman

Kimura

Fernandez

. Experiments on temporary obstruction of the internal auditory artery. Laryngoscope 1959; 69: 591–613.

Igarashi

Alford

Konishi

Shaver

Guilford

. Functional and histopathological correlations after microembolism of the peripheral labyrinthine artery in the dog. Laryngoscope 1969; 79: 603–23.

Lindsay

Hemenway

. Postural vertigo due to unilateral sudden partial loss of vestibular function. Ann Otol Rhinol Laryngol 1956; 65: 692–706.

Belal

Jr. Linthicum

Jr. House

. Middle fossa vestibular nerve section. A histopathological report. Am J Otol 1979; 1: 72–9.

House

Belal

Jr. . Translabyrinthine surgery. Anatomy and pathology. Am J Otol 1980; 1: 189–98.

Richter

. Quantitative study of human Scarpa's ganglion and vestibular sensory epithelia. Acta Otolaryngol (Stockh) 1980; 90: 199–208.

Van Buskirk

. The seventh nerve complex. J Comp Neurol 1945; 82: 303–33.

Hansen

. Vascular anatomy of the human temporal bone. I. Anastomoses between the membranous labyrinth and its bony capsule. Arch Otorhinolaryngol 1971; 200: 83–98.

10.

Walker

Jr. . The vertebro-basilar arterial system and internal auditory angiography. Laryngoscope 1965; 75: 369–407.

11.

Nabeya

. A study in the comparative anatomy of the blood-vascular system of the internal ear in mammalia and in homo (Japanese). Acta Sholae Med Univ Imp Kyoto 1923; 6: 1–132.

12.

Mazzoni

. Internal auditory canal arterial relations at the porus acusticus. Ann Otol Rhinol Laryngol 1969; 78: 797–814.

13.

Williams

Wilson

. The diagnosis of the major and minor syndromes of basilar insufficiency. Brain 1962; 85: 741–74.

14.

Kimura

Perlman

. Extensive venous obstruction of the labyrinth. A. Cochlear change. Ann Otol Rhinol Laryngol 1956; 65: 332–51.