Abstract
Bronchoscopic aspiration of the tracheobronchial tree in patients with cystic fibrosis is a controversial procedure. Results of therapy are difficult to evaluate. Many different techniques have been described, adding to the confusion. Our experience using limited lavage with 4% acetylcysteine and saline have been most gratifying in 114 procedures at the Children's Hospital Medical Center of Akron, Ohio. Each was performed under general anesthesia using the rigid bronchoscope. There were no deaths. Timing of the procedure and patient selection are partially subjective. The most impressive results have been improved pulmonary compliance and improved quality of life in the patient. Details of the procedure, techniques of anesthesia, and results of therapy are presented.
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