Abstract
Bronchoscopic cryotherapy of localized endobronchial tumors can be applied in selected patients who are not candidates for other traditional therapy. Twenty-eight patients were treated on 60 occasions with a closed liquid nitrogen system and a long insulated probe that was specifically designed to be used through an open ventilating bronchoscope. The condition of 15 patients (54 %) was improved, as judged by local tumor control, decreased bleeding, or improved airway patency. Fatal complications that could be ascribed to cryotherapy occurred in 2 of the 60 treatments (3 %). Two patients have experienced complete control of squamous cell cancers four years and five years nine months after cryotherapy.
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