The magnitude of initial response and slope of continued response of 45 neurons in the vestibular nuclei of cats to constant and interrupted accelerations were investigated. Eighty-eight percent exhibited adaptation, the magnitude of which was proportional to the stimulus. Comparison of slope and intercept of the response to continuous acceleration before and after a superimposed inhibitory velocity change suggests that the adaptation phenomenon is unrelated to cupular position.
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References
1.
Van EgmondAAJGroenJJJonkeesLBW. The mechanics of the semicircular canal. J Physiol1949; 110: 1–17.
2.
GroenJJLowensteinDVerdrikAJH. The mechanism of the responses from the end-organs of the horizontal semicircular canal in the isolated elasmobranch labyrinth. J Physiol1952; 117: 329–46.
3.
GroenJJ. On the semicircular canal system of the organs of equilibrium. Phys Med Biol1956–57; 1: 225–42.
HallpikeCSHoodJD. Fatigue and adaptation of the cupular mechanism of the human horizontal semicircular canal: An experimental investigation. Proc R Soc Lond [Biol]1953; 141: 542–61.
6.
HoodJD. The neurophysiological significance of cupular adaptation and its significance upon Ewald's second law. Acta Otolaryngol (Stockh)1961; Suppl 159.
GuedryFE. Psychophysiological studies of vestibular function. In: NeffWD. Contributions to sensory physiology. New York: Academic Press, 1975: 63.
9.
GillinhamKK. The effect of cerebellectomy of vestibular nuclear adaptation. Ann Otol Rhinol Laryngol1970; 79: 124–37.
10.
CramptonGH. Certain single cell responses within the vestibular nuclei of cat have characteristics which may be related to secondary nystagmus. In: HoodJD. Vestibular mechanisms in health and disease. New York: Academic Press, 1978: 59–65.
11.
PrechtWLlinasRClarkM. Physiological responses of frog vestibular fibers to horizontal angular rotation. Exp Brain Res1971; 3: 378–407.
12.
GoldbergJMFernandezC. Physiology of peripheral neurons innervating semicircular canals of the squirrel monkey. I. Resting discharge and response to constant angular accelerations. J Neurophysiol1971; 34: 635–60.
13.
BlanksRHIEstesMSMarkhamCH. Physiologic characteristics of vestibular first-order canal neurons in the cat. II. Response to constant angular acceleration. J Neurophysiol1975; 38: 1250–68.
14.
YoungCROmanGM. A model for vestibular adaptation to horizontal rotation. Aerospace Med1969; 40: 1076–80.
15.
MalcolmRMelvill-JonesG. A quantitative study of vestibular adaptation in humans. Acta Otolaryngol (Stockh)1970; 70: 126.
16.
ShimazuHPrechtW. Tonic and kinetic responses of cats vestibular neurons to horizontal angular acceleration. J Neurophysiol1965; 28: 991–1013.