The organ of Corti in the five-month human fetus was studied by transmission and scanning electronmicroscopy. Differentiation of the surface organization of the organ of Corti into a single row of inner and three to four rows of outer hair cells was complete at this stage except at the apical end. The morphological aspects of the hair bundles changed with maturation of the sensory cells; the inner hair cells preceded the outer hair cells in cytodifferentiation at a given location.
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References
1.
FriedmannI: Electron microscopic observations on in vitro culture of the isolated fowl otocyst. J Biophys Biochem Cytol5: 263–268, 1959.
2.
KikuchiKHildingDA: The development of the organ of Corti in the mouse. Acta Otolaryngol (Stockh)60: 207–222, 1965.
HildingDA: Electron microscopy of the developing hearing organ. Laryngoscope70: 1691–1704, 1969.
5.
PujolRHildingDA: Anatomy and physiology of the onset of auditory function. Acta Otolaryngol (Stockh)76: 1–10, 1973.
6.
Van De WaterTRHeywoodP: The in vitro development of innervated sensory hair cells of a mammal. Acta Otolaryngol (Stockh)82: 337–342, 1976.
7.
ThornL: Die Entwicklung des Cortischen Organs beim Meerschweinchen. Adv Anat Embryol Cell Biol51: 7–94, 1976.
8.
MarovitzWFKhanKMSchulteT: Ultrastructural development of the early rat otocyst. Ann Otol Rhinol Laryngol86 (Suppl 35: 9–28) 1977.
9.
HinojosaR: A note on development of Corti's organ. Acta Otolaryngol (Stockh)84: 238–251, 1977.
10.
Vasquez-NinGHSoteloJR: Electron microscope study of the developing nerve terminals in the acoustic organs of the chick embryo. Z Zellforsch Mikrosk Anat92: 325–338, 1968.
11.
OrrMF: A light and electron microscopic study of the embryonic chick otocyst. Dev Biol47: 325–340, 1975.
12.
NakaiY: An electron microscopic study of the human fetus cochlea. Pract-Oto-Rhino Laryngol32: 257–267, 1970.
13.
BredbergGAdesHWEngströmH: Scanning electron microscopy of the normal and pathologically altered organ of Corti. Acta Otolaryngol (Stockh)Suppl 301: 3–48, 1972.
14.
KushidaH: A new method for embedding in a low viscosity resin “Quetol 651.”J Electron Microsc23: 197, 1974.
15.
LindemanHAdesHWBredbergG: The sensory hairs and the tectorial membrane in the development of the cat's organ of Corti. Acta Otolaryngol (Stockh)72: 229–242, 1971.
16.
KimuraRSchucknechtHFSandoI: Fine morphology of the sensory cells in the organ of Corti in man. Acta Otolaryngol (Stockh)58: 390–408, 1964.
17.
TanakaKSmithCA: Structure of the chicken's inner ear: SEM and TEM study. Am J Anat153: 251–272, 1978.
18.
WersällJFlockA: Morphological aspects of cochlear hair cell physiology, in GrahamAB (ed): Sensorineural Hearing Processes and Disorders. Henry Ford Hospital International Symposium3, Boston, Little, Brown & Co.1967.
19.
SzaboT: Ultrastructural evidence for a mechanoreceptor function of the ampullae of Lorenzini. J Microsc14: 343–350, 1972.
20.
KimuraR: Hairs of the cochlear sensory cells and their attachment to the tectorial membrane. Acta Otolaryngol (Stockh)61: 55–72, 1965.
21.
RetziusG: Das Gehörorgan der Wirbeltiere-II. Das Gehörorgan der Reptilien, der Vögel und der Säugetiere.Stockholm, Samson & Wallin, 1884.
22.
OrrMF: Histogenesis of sensory epithelium in reaggregates of dissociated embryonic chick otocysts. Dev Biol17: 39–54, 1968.
23.
RubenRJ: Development of the inner ear of the mouse: A radioautographic study of terminal mitoses. Acta Otolaryngol (Stockh)Suppl 220, 1967.
24.
BastTAnsonA: The Temporal Bone and the Ear.Springfield, Ill., Charles C. Thomas, 1947.
25.
BredbergG: The human cochlea during development and ageing. J Laryngol Otol81: 739–758, 1967.