Clinical Correlation of Anomalies of the Supraglottic Larynx with the Staged Sequence of Normal Human Laryngeal Development

Abstract

The clinical correlation of the authors' observations on human laryngeal development with existing literature supports the suggestion that earlier concepts, specifically by Frazer, may not be valid. It is further proposed that development of the human larynx may similarly correspond in man to that of the rat. Congenital laryngeal malformations are fundamentally associated with a disturbance of epithelial mesenchymal interactions, particularly related to a premature arrest of the normally vigorous epithelial activity.

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References

Tucker

: The infant larynx: Direct laryngoscopic observations. JAMA 99: 1899–1902, 1932.

Tucker

O'Rahilly

: Observations on the embryology of the human larynx. Ann Otol Rhinol Laryngol 81: 520–523, 1972.

O'Rahilly

Tucker

: The early development of the larynx in staged human embryos. Ann Otol Rhinol Laryngol 82 (Suppl 7: 3–27) 1973.

Tucker

Jr. : Some aspects of fetal laryngeal development. Ann Otol Rhinol Laryngol 84: 49–55, 1975.

Smith

: The early development of the trachea and esophagus in relation to atresia of the esophagus and tracheoesophageal fistula. Contrib Embryol Carnegie Inst 36: 41–57, 1957.

Streeter

: Developmental horizons in human embryos. Description of age group XI, 13 to 20 somites, and age group XII, 21 to 29 somites. Contrib Embryol Carnegie Inst 30: 211–245, 1942.

Soulie

Bardier

: Recherches sur le development du larynx chez l'homme. J Anat Physiol 43: 137–240, 1907.

Yokoh

: The early development of the nervous system in man. Acta Anat 71: 492–518, 1968.

Lisser

: Studies on the development of the human larynx. Am J Anat 12: 27–66, 1911.

10.

O'Rahilly

Boyden

: The timing and sequence of events in the development of the human respiratory system during the embryonic period proper. Z Anat Entwicklungsgesch 141: 237–250, 1973.

11.

Blumberg

Stevenson

Lemire

: Laryngotracheoesophageal cleft, the embryologic implications: Review of the literature. Pediatr Surg 57: 559–566, 1965.

12.

O'Rahilly

Bossy

: The growth of the eye in utero. An Desarrollo 16: 31–51, 1972.

13.

Holinger

Brown

: Congenital webs, cysts, laryngoceles and other anomalies of the larynx. Ann Otol Rhinol Laryngol 76: 744–752, 1967.

14.

Fearon

Ellis

: The management of long term airway problems in infants and children. Ann Otol Rhinol Laryngol 80: 669–677, 1971.

15.

Holinger

: Clinical aspects of congenital anomalies of the larynx, trachea, bronchi, and esophagus. J Laryngol Otol 75: 1–44, 1961.

16.

Turtz

Tucker

Jr. : The present day spectrum of pediatric bronchoesophagology. Laryngoscope 82: 945–955, 1972.

17.

Phelan

Gillam

Stocks

: The clinical and physiological manifestations of the ‘infantile’ larynx: Natural history and relationship to mental retardation. Aust Paediatr J 7: 135–140, 1971.

18.

Kelemen

: Congenital laryngeal stridor. Arch Otolaryngol 58: 245–268, 1953.

19.

Ward

Engel

Nance

: The larynx in the cri du chat (cat cry) syndrome. Trans Am Acad Ophthalmol Otolaryngol 72: 90–102, 1968.

20.

Healy

Holt

Tucker

: Bifid epiglottis: A rare laryngeal anomaly. Presented at Am Laryngol Rhinol Otol Society Inc, Canada, 1976.

21.

McHugh

Loch

: Congenital webs of the larynx. Laryngoscope, 52: 43–65, 1942.

22.

Holinger

Wong

Hemenway

: Simultaneous glottic and supraglottic laryngeal webs. Arch Otolaryngol 101: 496–497, 1975.

23.

Hannallah

Rosales

: Laryngeal web in an infant with tracheoesophageal fistula. Anesthesiology 42: 96–97, 1975.

24.

Hardingham

Walsh-Waring

: The treatment of a congenital laryngeal web. J Laryngol Otol 89: 273–279, 1975.

25.

Tucker

: Congenital web of the larynx. Arch Otolaryngol 21: 172–174, 1935.

26.

Shearer

Biller

Ogura

: Congenital laryngeal web and interventricular septal defect. Am J Dis Child 123: 605–607, 1972.

27.

Holinger

Johnston

: Factors responsible for laryngeal obstruction in infants. JAMA 143: 1229–1232, 1950.

28.

Seifert

: Ueber congenitale Membranbildung im Larynx. Berliner Klin Wchnschr 2: 24, 1889.

29.

Glas

: Ueber congenitale Kehlkopfdiaphramen und Faltenbildungen. Wien Klin Wchnschr 21: 603, 1908.

30.

Savetsky

: Congenital partial atresia of the larynx. Presented at Joint Mtg Eastern Section of Am Laryngol Rhinol Otol Society, Inc., January, 1966.

31.

McNaught

: Surgical correction of anterior web of the larynx. Laryngoscope 60: 264–272, 1950.

32.

Cohen

: Congenital atresia of the larynx with endolaryngeal surgical correction: A case report. Laryngoscope 81: 1607–1615, 1971.

33.

Smith II Bain

: Congenital atresia of the larynx. Ann Otol Rhinol Laryngol 74: 338–349, 1965.

34.

Fox

Cocker

: Laryngeal atresia. Arch Dis Child 39: 641, 1964.

35.

DeSanto

Devine

Weiland

: Cysts of the larynx — Classification. Laryngoscope, 80: 145–176, 1970.

36.

Suesh

Powell

: Congenital cysts of the larynx in infants. Laryngoscope, 77: 654–662, 1967.

37.

Holinger

Brown

: Congenital webs, cysts, laryngoceles and other anomalies of the larynx. Presented at 88th Ann Mtg Am Seigniory Club, Canada, May 15–16, 1967.

38.

Walpita

: Laryngocele in an infant. J Pediatr Surg 10: 843–844, 1975.

39.

Fearon

Cotton

: Surgical correction of subglottic stenosis of the larynx in infants and children. Progress report. Ann Otol Rhinol Laryngol 83: 428–431, 1974.

40.

Holinger

Kutnick

Schild

: Subglottic stenosis in infants and children. Ann Otol Rhinol Laryngol 85: 591–599, 1976.

41.

McMillan

Duvall

III : Congenital subglottic stenosis. Arch Otolaryngol 87: 70–76, 1968.

42.

Cundy

Bergstrom

: Congenital subglottic stenosis. J Pediatr 82: 282–284, 1973.

43.

Crysdale

Platt

: Division of posterior cricoid plate in young children with subglottic stenosis. Laryngoscope 86: 1451–1458, 1976.

44.

Parkin

Stevens

Jung

: Acquired and congenital subglottic stenosis in the infant. Ann Otol Rhinol Laryngol 85: 573–581, 1976.

45.

Fearon

Cotton

: Surgical correction of subglottic stenosis of the larynx. Preliminary report of an experimental surgical technique. Ann Otol Rhinol Laryngol 81: 508–513, 1972.

46.

Baker

: Chronic laryngeal stenosis. Ann Otol Rhinol Laryngol 78: 751–756, 1969.

47.

Burroughs

Leape

: Laryngotracheoesophageal cleft: Report of a case successfully treated and review of the literature. Pediatrics 53: 516–522, 1974.

48.

Cohen

: Cleft larynx. A report of seven cases. Ann Otol Rhinol Laryngol 84: 747–756, 1975.

49.

Fuzesi

Young

: Congenital laryngotracheoesophageal cleft. J Pediatr Surg 11: 933–937, 1976.

50.

Bell

Christiansen

Smith

: Laryngotracheoesophageal cleft: The anterior approach. Ann Otol Rhinol Laryngol 86: 616–622, 1977.

51.

Pillsbury

Fischer

: Laryngotracheoesophageal cleft. Diagnosis, management, and presentation of a new diagnostic device. Arch Otolaryngol 103: 735–737, 1977.

52.

Ferguson

Flake

: Subglottic hemangioma as a cause of respiratory obstruction in infants. Ann Otol Rhinol Laryngol 70: 1095–1112, 1961.

53.

Leikensohn

Benton

Cotton

: Subglottic hemangioma. J Otol 5: 487–492, 1976.

54.

Benjamin

: Treatment of infantile subglottic hemangioma with radioactive gold grain. Ann Otol Rhinol Laryngol 87: 18–21, 1978.

55.

Atkins

: Laryngeal problems of infancy and childhood. Pediatr Clin North Am 9: 1125–1135, 1962.

56.

Walander

: Prenatal development of the epithelial primordium of the larynx in the rat. Acta Anat 10: 1–140, 1950.

57.

Holinger

Johnston

Schiller

: Congenital anomalies of the larynx. Ann Otol Rhinol Laryngol 63: 581–606, 1954.

58.

Jackson

: Bronchoscopy, Esophagoscopy and Gastroscopy. Philadelphia, WB Saunders, 1934.

59.

Holinger

Zimmerman

Parchet

: A correlation of the embryonic development of the trachea and lungs with congenital malformations. Adv Otol Rhinol Laryngol 3: 1–40, 1955.

60.

Gruenwald

: A case of atresia of the esophagus combined with tracheoesophageal fistula in a 9 mm human embryo and its embryologic explanation. Anat Rec 78: 293, 1940.

61.

Walander

: The mechanism of origin of congenital malformations of the larynx. Acta Otolaryngol (Stockh) 45: 426–432, 1955.

62.

Alescio

Piperno

: A quantitative assessment of mesenchymal contribution to epithelial growth rate in mouse embryonic lung developing in vitro. J Embryol Exp Morph 17: 213–227, 1967.

63.

Taderera

: Control of lung differentiation in vitro. Develop Biol 16: 489–512, 1967.

64.

Goedbloed

: La differenciation precoce des regions branchiales chez 1' embryon humain. C R Assn Anat 46: 304–309, 1959.

65.

Frazer

: The development of the larynx. J Anat Physiol 44: 156–191, 1910.