A brief review of chronic granulomatous disease, an immunological and clinical entity, is presented. The clinical and laboratory findings are listed and hereditary aspect discussed briefly. The futility of treatment is mentioned. A case is reported in which laryngeal destruction and bronchial obstruction had been due to this disease.
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References
1.
BerendesHBridgesRAGoodRA: A fatal granulomatosis of childhood. Minn Med40: 309, 1957.
2.
BridgesRABerendesHGoodRA: A fatal granulomatous disease of childhood. Amer J Dis Child97: 387, 1959.
3.
HolmesBQuiePGWindhorstDE: Fatal granulomatous disease of childhood. Lancet1: 1255, 1966a.
4.
QuiePGWhiteJGHolmesB: In vitro bactericidal capacity of human polymorphonuclear leukocytes. J Clin Invest46: 668, 1967.
5.
KaplanELLaxdalTQuiePG: Studies of polymorphonuclear leukocytes from patients with chronic granulomatous disease of childhood. Pediatrics41: 591, 1968.
6.
HolmesBPageARGoodRA: Studies of the metabolic activities of leukocytes from patients with a genetic abnormality of phagocytic function. J Clin Invest46: 1422, 1967.
ParkBHGoodRA: NBT test stimulated. Lancet2: 616, 1970.
13.
WindhorstDBPageARHolmesB: The pattern of genetic transmission of the leukocyte defect in fatal granulomatous disease of childhood. J Clin Invest47: 1026, 1968.
14.
GoodRA: Progress towards a cellular engineering. JAMA214: 1289, 1970.
