Cryosurgery may be used as primary treatment for T1 cancer of the larynx in elderly patients with fair or poor medical status and as secondary treatment in postradiation failures of T1 carcinoma, or in multicentric carcinoma in situ. It is of proven value in cases studied to date. Many properly classified patients are being treated by this method with the expectation that most will not require a laryngectomy. Recurrent squamous papillomata of the larynx have responded excellently in many patients with cryosurgery, some necessitating more treatment than others. Fewer laryngoscopies are necessary; in most patients, the disease was eliminated in one to five treatments.
Get full access to this article
View all access options for this article.
References
1.
GoldsteinJC: Cryotherapy in head and neck cancer. Laryngoscope80: 1046–1052, 1972.
2.
LundquistPGIgarashiMWersallJ: Effects of cryosurgery on vestibular sensory epithelia in the guinea pig. Arch Otolaryng95: 530–542, 1972.
3.
ShermanJKKimKS: Correlation of ultrasrrucrure before freezing, while frozen and after thawing in assessing freeze-thaw induced injury. Cryobiology4: 16, 1967.
4.
MillerDSilversteinHSchwarzJ: Histopathological studies of the larynx after cryosurgery, to be published.
5.
MillerDMetznerD: Tissue penetration studies using liquid nitrogen. Trans AAOO73: 300–309, 1969.
6.
MillerD: Three years experience with cryosurgery in head and neck rumors. Ann Otol78: 786, 1969.
7.
MillerD: Cryosurgery for the treatment of neoplasms of the oral cavity. Otolaryngologic Clinics of North America5: 377–388, 1972.
8.
OguraJHBillerHF: Preoperative irradiation for laryngeal and laryngopharyngeal cancers. Laryngoscope80: 802, 1970.
9.
KirchnerFRSmithSAToledoPS: Micro cryocauterization of papillomas of the larynx. Trans AAOO75: 513–518, 1971.
