Castleman's disease is a rare, benign disease of unknown cause that induces reactive lymph node hyperplasia, most commonly in the mediastinum. It has 2 histologic subtypes: hyaline vascular and plasma cellular. A definitive diagnosis necessitates tissue biopsy. A specimen may be even misdiagnosed as lymphoma in frozen section. Surgery is the treatment of choice for the solitary form, whereas chemotherapy, radiotherapy, and steroids are proposed for the multicentric type. A neck mass diagnosed as Castleman's disease in a 48-year-old woman is reported.
DangoorEElidanJGomoriJMDanoI. Castleman's disease of the retropharynx: A benign tumor in a 12-year-old girl. Am J Otolaryngol1998; 19: 194–7.
3.
BowneWBLewisJJFilippaDA. The management of unicentric and multicentric Castleman's disease: A report of 16 cases and a review of the literature. Cancer1999; 85: 706–17.
4.
AltinliEPekmezciSBalkanT. Castleman's disease masquerading as sigmoid colon tumor and Hodgkin lymphoma. Swiss Surg2002; 8: 7–10.
5.
OttavianiFGalliJDi GirolamoSAlmadoriG. Castleman's disease restricted to the parapharyngeal space. J Otolaryngol1999; 28: 95–8.
6.
ChoiGLeeUKimAChoiJO. Castleman's disease of the parotid gland. J Otolaryngol1997; 26: 319–21.
7.
KellerARHochholzerLCastlemanB. Hyaline-vascular and plasma-cell types of giant lymph node hyperplasia of the mediastinum and other locations. Cancer1972; 29: 670–83.
8.
KooperDPTiwariRMvan der ValkP. Castleman's disease as an uncommon cause of a neck mass. Eur Arch Otorhinolaryngol1994; 251: 370–2.
9.
OsmaUCureogluSYaldizMTopcuI. Castleman's disease (giant lymph node hyperplasia) of the neck: A case report. Eur Arch Otorhinolaryngol2001; 258: 42–4.
BoxerLABoxerGJFlairRCEngstromPFBrownGS. Angiomatous lymphoid hamartoma associated with chronic anemia, hypoferremia, and hypergammaglobulinemia. J Pediatr1972; 81: 66–70.
12.
ArslanDOzturkFPatirogluTKucukaydinMGunduzZ. Castleman's disease. A case report. Turk J Pediatr1996; 38: 361–6.
13.
UcuncuHAktanBKarasenEAltasNGursanNSirinS. Castleman disease. Turk Arch Otolaryngol1997; 35: 115–7.
14.
YiAYdeTarMBeckerTSRiceDH. Giant lymph node hyperplasia of the head and neck (Castleman disease): A report of five cases. Otolaryngol Head Neck Surg1995; 113: 462–6.
15.
PenfoldCNCottrellBJTalbotR. Neonatal giant lymph node hyperplasia (Castleman's disease) presenting in the head and neck. Br J Oral Maxillofac Surg1991; 29: 110–1.
16.
ShermanJABirtwhistleCJDaviesHT. A rapidly expanding lesion in the neck: Unusual presentation of Castleman's disease. Int J Oral Maxillofac Surg2001; 30: 458–60.
17.
PatelUForteVTaylorGSirkinW. Castleman's disease as a rare cause of a neck mass in a child. J Otolaryngol1998; 27: 171–3.
18.
SanzCSierraJCobarroJAvellanedaRMontserratERozmanC. An unusual case of Castleman's disease restricted to the neck. ORL J Otorhinolaryngol Relat Spec1992; 54: 331–3.
