Congenital antithrombin III deficiency is an uncommon but important cause of venous thrombosis, usually presenting with recurrent or atypical venous throm boembolism. Its importance lies in the fact that early recognition can lead to treatment in the acute stage, which can prevent propagation of the disease, and further prophylactic treatment may reduce the incidence of further episodes. The authors present a case of mesenteric venous infarction associated with congeni tal antithrombin III deficiency and briefly discuss the diagnosis, surgical impli cations, and treatment of this disorder.
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References
1.
Cosgriff TM, Bishop DT, Hershgold EL, et al: Familial antithrombin III deficiency. Its natural history, genetics, diagnosis and treatment. Medicine62:209-218, 1983.
2.
Maung R., Kelly JK, Schneider MP, et al: Mesenteric venous thrombosis due to antithrombin III deficiency .
3.
Vikydal R., Korninger C., Kyrle PA, et al: The prevalence of hereditary antithrombin III deficiency in patients with a history of venous thromboembolism. Thromb Haemost54:744-745, 1985.
4.
Karl R., Garlick I., Zarins C., et al: Surgical implications of antithrombin III deficiency. Surgery89:429-432, 1981.
