The patients at high risk of deep venous thrombosis are defined. Factors in the formation of intravenous thrombi are described. The roles of endothelium, formed elements, clotting factors, and their interrelationships are correlated. Diagnostic modalities and their application are described, and the commonly used medical and surgical therapies are specifically outlined.
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References
1.
Hamer JD, Malone PC, Silver IA: The PO2 in venous valve pockets. Br J Surg68:166-190, 1981.
2.
Hamer JD, Malone PC: Experimental deep vein thrombogenesis by a non-invasive method. Ann R Coll Surg66:416-424, 1980.
3.
Takeshi K., Mineo M.: Flow through a venous valve and its implication for thrombosis formation. Thromb Res36:245-257, 1984.
4.
Gwendolyn J. , Stewart J., Reichle FA, et al: The adhesion of leukocytes, erythrocytes, and noncellular material to the luminal surface of natural and artificial blood vessels in vivo. Ann NY Acad Sci10: 179-207.
5.
Mellbring G. , Dahgran S., Reitz S., et al: Fibrolytic activity in plasma in deep venous thrombosis after major abdominal surgery. Thromb Res32:575- , 1983.
6.
Wiman B., Lyanberg B., Chimielewskan J., et al: The role of the fibrinolytic system in deep vein thrombosis . J Lab Clin Med105:265-270, 1985.
7.
Alman T., Nylander G.: Phlebography of the lower leg during muscular contraction and relaxation. Acta Radiol57:264-270, 1962.
8.
Hull R., Hirsch J., Sockett D., et al: The values of adding importance plethysmography to 125 scanning for the detection of deep vein thrombosis in high risk surgical patients. Thromb Res5:227-234, 1979.
9.
Hull R., Taylor W., Hirsh J., et al: Impedance plethysmography: The relationship between venous filling and sensitivity and specificity for proximal vein thrombosis. Circulation58:898-902, 1978.
10.
Wheeler HB, Anderson FA Jr: The diagnosis of venous thrombosis by impedence plethysmography. In: Noninvasive Diagnostic Techniques in Vascular Disease, 3rd ed, ed. by Bernstein EF.St. Louis: CV Mosby, 1985, p 775.
11.
Diserio FJ, Sasahara AA: U.S. trial of dehydroergotamine and heparin prophylaxis of deep vein thrombosis . Am J Surg150(4A):25-32, 1985.
12.
Kakkar VV, Wetzel D., Murray Wjg, et al: Possible mechanism of the synergistic effect of heparin and dehydroergotamine. Am J Surg150(4A):33-38, 1985.
13.
Koppenhagen K., Haring R.: Verglierchande Untersuchen Zeulichen, Heparin Ergotamine 2500 and low dose Heparin. Klinikarzt10:782-786, 1981.
14.
Rem et al: Complications of thromboembolic prophylaxis with heparin and dihydroergotamine , Lancet1:219, 1987.
15.
Gattner R.: Complication of thromboembolic prophylaxis with heparin and dihydroergotamine , Lancet2:838-839, 1986.
16.
Kakkar VV, Lawrence D.: Hemodynamic assessment after therapy for acute deep vein thrombosis. Am J Surg150(4A):55-63, 1985.
17.
Hess H., Mietaschk AB, Niki R.: Peripheral arterial occlusions: 6 years' experience with local low dose thrombolytic therapy. Radiology163:753-758, 1987.
18.
Persson AV, Robichaux WT, Jaxheimer EC, et al: Burst therapy: Fibrinolytic agents. Am J Surg147:531-536, 1984.
19.
Persson AV, Persson CA: Thombolytic therapy for deep venous thrombosis. Am J Surg150(4A):50-54, 1985.
20.
Spencer FC, et al: Plication of inferior vena cava for pulmonary emboli: Report of 20 cases. Am J Surg155:821-837, 1962.
21.
DeWeese MS, Hunter DC Jr: A vena cava filter for the prevention of pulmonary emboli. Bull Soc Int de Chir1:17-25, 1958.
22.
Moretz WH, Naisbitt PF, Stevenson GP: Experimental studies of temporary occlusion of the vena cava. Surg36:384-398, 1954.
23.
Moretz WH, Rhode CM, Shepard MH: Prevention of pulmonary emboli by partial occlusion of the inferior vena cava . Am Surg25:617-627, 1959.
24.
Mobin-Udin, et al: A venal caval filter for the prevention of pulmonary embolism. Surg Forum10:209-267, 1967.
25.
Greenfield LJ, McCurdy JR, Brown PP, et al: A new intracaval filter permitting continued flow and resolution of emboli. Surgery73:599-606, 1973.
26.
Greenfield LJ, McCurdy JR, Brown PP, et al: A new intraval filter permitting continued flow and resolution of emboli. Surgery73:599-606, 1973.
27.
Greenfield LJ, Stewart JR, Crute S.: Improved technique for Greenfield vena caval filter insertion. Surg Gynecol Obstet156:217-219, 1983.
28.
Mavor GE, Galloway JM: The iliofemoral segment as a source of pulmonary emboli. Lancet1:871-874, 1967.
29.
Goto H., Wada T., Matsumoto A., et al: Iliofemoral venous thrombectomy. J Cardiovasc Surg21:341-346, 1980.
30.
Roder OC, Lorentzen JE, Hansen Hjb: Venous thrombectomy for iliofemoral thrombosis. Acta Chir Scand150:31-35, 1984.
31.
Smith DE, Trimble C.: Surgical management of obstructive venous disease of the lower extremity. In: Vascular Surgery, ed. by Rutherford RB.Philadelphia: WB Saunders1977, pp 1247-1268.
32.
DeWeese JA, Jones TI, Lyon J., et al: Evaluation of thrombectomy in the management of iliofemoral venous thrombosis. Surgery47:140-159, 1960.
33.
Fogarty TJ, Dennis D., Kripaehne WW: Surgical management of iliofemoral venous thrombosis. Am J Surg112:211-217, 1966.
34.
Kirstner RL : Surgical repair of the incompetent femoral vein valve. Arch Surg110: 1336-1342, 1975 .
35.
Palma EC, Esperon R.: Vein transplants and grafts in the surgical treatment of the postphlebitic syndrome. J Cardiovasc Surg1:94-97, 1960.
36.
Kirstner RL , Sparkuhl MD: Surgery in acute and chronic venous disease . Surgery85:31-43, 1979.
37.
Warren K., Thayer TR: The transplantation of the saphenous vein for postphlebitic stasis. Surgery35:867-876, 1954.
38.
Dale WA: Venous bypass surgery. Surg Clin N Am62:391-398, 1982.
39.
Husni EA: In situ saphenopopliteal bypass graft for incompetence of the femoral and popliteal veins. Surg Gynecol Obstet130:279-284, 1970.
40.
Husni EA: Reconstruction of veins: The need for objectivity. J Cardiovasc Surgery24:525-528, 1983.
41.
Kistner RL: Surgical repair of the incompetent femoral vein valve. Arch Surg110:1336-1342, 1975.
42.
Kistner RL, Sparkuhl RD: Surgery in acute and chronic venous disease. Surgery85:31-45, 1979.
43.
Kistner RL: Primary venous valve incompetence of the leg. Am J Surg140:218-224, 1980.
44.
Taheri SA, Lazar L., Elias SM, et al: Vein valve transplantation. Surgery91:28-33, 1982.