Data from 2,298 measurements of pulmonary venous admixture (QS/QT) per formed in 733 patients were analyzed and processed in order to develop a method for rapid and reliable estimation of QS/QT by a simplified approach. Formulae and charts were obtained, which are easily suitable for use in all settings, and permit estimation of QS/QT with an 85%-93% control of its varia bility (r2 = 0.85-0.93, p < 0.0001) simply on the basis of the measured arterial and central venous O2 tensions or saturations.
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References
1.
Siegel JH, Giovannini I., Coleman B.: Ventilation/perfusion maldistribution secondary to the hyperdynamic cardiovascular state as the major cause of increased pulmonary shunting in human sepsis. J Trauma19:432-460, 1979.
2.
Siegel JH, Giovannini I., Coleman B., et al: Death after portal decompressive surgery: Physiologic state, metabolic adequacy and the sequence of development of the physiological determinants of survival. Arch Surg116:1330-1341, 1981 .
3.
Giovannini I. , Boldrini G., Chiarla C., et al: Adequacy and support of physiological functions in the acutely ill cirrhotic patient. World J Surg11:202-209, 1987.
4.
Sackur P.: Weiteres zur Lehre vom Pneumothorax. Virchows Arch Patol Anat Physiol150:151-170, 1897.
5.
Berggren SM: The oxygen deficit of arterial blood caused by nonventilating parts of the lung. Acta Physiol Scand11 (Suppl): 1-45, 1942.
6.
Giovannini I. , Boldrini G., Sganga G., et al: Quantification of the determinants of arterial hypoxemia in critically ill patients. Crit Care Med11:644-645, 1983.
7.
Giovannini I. , Boldrini G., Castagneto M., et al: Reference sources and computational data for cardiorespiratory monitoring by mass spectrometer in critically ill patients. Spectros Int J3:401-407, 1984.
8.
Comroe JH Jr, Forster RE, Du Bois AB, et al: The Lung. Chicago: Year Book Medical Publisher, 1962.
9.
Kelman GR: Digital computer subroutine for the conversion of oxygen tension into saturation . J Appl Physiol21:1375-1379, 1966 .