Of all the controversial topics in the management of cerebrovascular dis eases the subject of transient ischemic attacks is perhaps the most controver sial. A preponderance of literature related to the subject, reflecting a remarka ble degree of interest in the topic, is a result of this controversy. Each conclu sion serves to stimulate more interest, more evaluation, and more controversy. We will attempt to give an overview of the controversies in the management of transient ischemic attacks.
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References
1.
Youmans JR: Cerebral blood flow in clinical problems. In: Neurological Surgery. Philadelphia, Saunders , 1973, p. 800.
2.
Lassen NA and Christensen MS: Physiology of cerebral blood flow. Br J Anaesth48:719, 1976.
3.
Symon L., Crockard HA, Dorsch Nwc, et al: Local cerebral blood flow and vascular reactivity in a chronic stable stroke in baboons. Stroke6:482, 1975.
4.
Astrup J., Symon L., Branston NM, et al: Cortical evoked potential and extracellular K+ and H+ at critical levels of brain ischemia. Stroke8:51, 1977.
5.
Greenberg RP : Noninvasive localization of brain stem lesions in cat with multimodal evoked potentials. J Neuro Surg54:740-750, 1981.
6.
Shaller CA, Jacques S. and Shelden CH: The pathophysiology of stroke: A review with molecular considerations. Surg Neurol14:433-442, 1980.
7.
Austin G., Haugen G. and Brown D.: Mitochondrial respiration following microanastomosis for brain ischemia (Abstract) . Proceedings of the American College of Surgeons, Jan 16, 1977.
8.
Slade WR: Diagnosis and evaluation of transient ischemic attacks. Prac Cardiology6:51-61, 1980.
9.
Millikan CH: Transient cerebral ischemia: Definition and natural history. Prog Cardiovasc Dis22(5):303-308, 1980.
10.
Simonsen N. , Dalgas C., Heltberg A., et al: Long term prognosis after transient ischemic attacks. Acta Neurol Scand63:156-168, 1981.
Millikan CH: The pathogenesis of transient focal ischemia. Circ32:438-450, 1965.
13.
Millikan CH and McDowell FH: Treatment of transient ischemic attacks. Stroke9:299-308, 1978.
14.
Whisnant JP, Matsumoto N. and Elveback LR: The effect of anticoagulant therapy on the prognosis of patients with transient cerebral ischemia in a community, Rochester, Minnesota 1955-1969. Mayo Clin Proc48:194-198, 1973.
Fields WS, Maslenikov V., Meyer JS, et al: Joint study of extracranial arterial occlusion. V. Progress report of prognosis following surgery or non-surgical treatment for transient cerebral ischemic attacks and cervical carotid artery lesions. JAMA211:1993-2003, 1970.
17.
Thompson JE: Surgery for Cerebrovascular Insufficiency (Stroke). Springfield, Ill, Charles C. Thomas, 1968.
18.
Acheson J. and Hutchinson EC: The natural history of focal cerebral vascular disease. Q J Med40:15, 1971.
19.
Siekert RG, Whisnant JP, Millikan CH: Surgical and anticoagulant therapy of occlusive cerebral vascular disease . Ann Intern Med58:637-641, 1963.
Fields WS, Lemak NA, Frankowski RF, et al: Controlled trial of aspirin in cerebral ischemia Part II Surgical Group. Stroke9:309-319, 1978.
22.
Heyman A.: Transient focal cerebral ischemia: Epidemiological and clinical aspects. In: Fundamentals of Stroke Care, ed. by Sahs AL, Hartman EC.Washington, DC: Health resources administration, 1976, pp. 33-40.
23.
Adams HPJr: Transient ischemic attacks differentiation and treatment. Post Graduate Med69:157-166, 1981.
24.
Mohr JP: Transient ischemic attacks and the prevention of strokes. NEJM299:93-95, 1978.
25.
Baker RN, Ramseyer JC, Schwartz W.: Prognosis in patients with transient cerebral ischemic attacks. Neurology18:11-47, 1968.
26.
Calanchini PR, Swanson PD, Gotshall RA, et al: Cooperative study of hospital frequency and character of transient ischemic attacks IV Reliability of diagnosis. JAMA238:2029-2033, 1977.
27.
Ackerman RH : A perspective on noninvasive diagnosis of carotid disease. Neurology29:615-622, 1979.
28.
Sandok BA: Noninvasive techniques for diagnosis of carotid artery disease. Stroke9:427-429, 1978.
29.
Baker WH and Barnes RW: The cerebrovascular doppler examination in patients with non-hemispheric symptoms . Ann Surg186:190-192, 1977.
30.
Gross WS, Verta MJ Jr, VanBellex B. et al: Comparison of non-invasive diagnostic techniques in carotid artery occlusive disease. Surg82:271-278, 1977.
31.
Bone GE and Barnes RW: Clinical implications of the doppler cerebrovascular examination: A correlation with angiography. Stroke7:271-274, 1976.
McDonald PT , Rich NM, Collins GJ, et al: Doppler cerebrovascular examination, oculoplethysmography and ocular pneumoplethysmography. Arch Surg113:1341-1349, 1978.
34.
Towne JB, Salles-Cunha S., Bernhard VM: Periorbital ultrasound finding. Hemodynamics in patients with cerebral vascular disease. Arch Surg114:158-160, 1979.
35.
Meyer JS and Methew NT: Medical management in cerebral ischemia. In: Controversies in Internal Medicine, II, ed. by Ingelfinger FJ, Ebert RV, Finland M, et al. Saunders, 1977, pp. 771-786.
36.
Tognomi G. and Garattini S.: Drug treatment and prevention in cerebrovascular disorders: Proceedings of the international seminar on drug treatment and prevention in cerebrovascular disorders, Milan, Italy, May 2-4, 1979. Amsterdam, New York, Elbevier/ North-Holland Biomedical Press, 1979.
37.
Millikan CH: Anticoagulant or surgical treatment of cerebral ischemia. In: Controversies in Internal Medicine, II, ed. by Ingelfinger FJ, Ebert RV, Finland M, et al. Saunders, 1974, pp. 787-803.
38.
Dykew ML, Conneally PM, Hearer AF, et al: Cooperative study of hospital frequency and character of transient ischemic attacks. I. Background, organization and clinical study. JAMA237:882-886, 1976.
39.
Mankowitz C. and Taylor JM: A modem view of the surgical treatment of peripheral arterial disease: A critical response. JAMA241:1467-1468, 1979.
40.
Toole JF, Yuson CP, Janeway R., et al: Transient ischemic attacks: A prospective study of 225 patients . Neurology28:746-753, 1978.
41.
Rice PL, Piffarre R., Sullivan NJ, et al: Experience with simultaneous myocardial revascularization and carotid endartectomy. J Thorac Cardiovasc Surg79:922-925, 1980.
42.
Mehigan JT, Buch WS, Pipkin RD, et al: A planned approach to coexistent cerebrovascular disease in coronary artery bypass candidates. Arch Surg112:1403-1409, 1977.
43.
Kurtzke J.: Formal discussion on "Effect of duration of treatment with anticoagulants on the prognosis of transient cerebral ischemic attacks," In: Cerebral Vascular Diseases, ed. by Whisnant JP and Sandok BA.N.Y., Grune and Stratton, 1975, pp. 190-193.
44.
Duke LJ, Slaymaker EE, Lamberth WC Jr, et al: Carotid artery reconstruction: Ten-years experience. Am Surg45:281-288, 1969.
45.
Allen GS, Cohen RJ and Preziosi TJ: Microsurgical endarterectomy of the intracranial vertebral for vertebrobasilar transient ischemic attacks. Neurosurg8:56-9, 1981.
46.
Sampson DS, Hodosh RM and Clark WK: Microsurgical treatment of transient cerebral ischemia: Preliminary results in 50 patients. JAMA241:376-8, 1979.
47.
Silver D.: Complications and failure of anticoagulant therapy. In: Complications in Vascular Surgery, ed. by Bernhard WM and Towne JB.New York, Grune and Stratton, 1980, pp. 461-474.
48.
Sandok BA, Furian AJ, Whisnant JP, et al: Guidelines for the management of transient ischemic attacks . Mayo Clinic Proc53:665-674, 1978.
49.
Millikan CH : Anticoagulant treatment to prevent cerebral infarction. Med Clin NA 63:897-904, 1979.
50.
Herskovits E., Vasquez A., Famuluri A., et al: Randomized trials of pentoxifylline versus acetylsalicic acid plus dipyridamole in preventing transient ischemic attacks. Lancet1:966-968, 1981.
51.
Hirsh J.: Selection and results of antiplatelet therapy in the prevention of stroke and myocardial infarction. Arch Intern Med141:311-315, 1981.
52.
Aspirin Myocardial Infarction Study Research Group — A randomized controlled trial of aspiring in persons recovered from myocardial infarction. JAMA243:661-669, 1980.
53.
Persantine-Aspirin Reinfarction Study Group — Persantine and aspiring in coronary heart disease . Circ62:449-461, 1980.
54.
CanadianCooperative Study Group — A randomized trial of aspirin and sulfinpyrazone in threatened stroke. NEJM299:53-59, 1978.
55.
Anturane Reinfarction Trial Research Group — Sulfinpyrazone in the prevention of cardiac death after myocardial infarction. The anturane reinfarction trial. NEJM298:289-295, 1978.
56.
Kelton JC, Hirsh J., Carter CJ, et al: Sex differences in the antithrombotic effects of aspirin. Blood52:1073-1076, 1978.
57.
Brewster DC , Schlaen HH, Raines J.K., et al: Rational management of the asymptomatic carotid bruit. Arch Surg113:927-930, 1978.
58.
Thompson JE , Patman RD and Persson AV: Management of asymptomatic carotid bruits . Am Surg42:77-89, 1976.
59.
Kartchner MM and McRae LP: Noninvasive evaluation and management of the "asymptomatic" carotid bruit. Surg82:840-847, 1977.
60.
Moore WS, Boren C., Malone JM, et al: Natural history of nonstenotic asymptomatic ulcerative lesions of the carotid artery. Arch Surg113:1352-1359, 1978.
61.
Machleder HI : Strokes, transient ischemic attacks and symptomatic bruits. West J Med130:205-207, 1979.
62.
Wolf PA, Kannel WB, Surlie P., et al: Asymptomatic carotid bruit and risk of stroke. The Framingham study. JAMA245:1442, 5, 1981.