Abstract
Modified isotope clearance tests for the objective investigation of inter mittent claudication of the lower limb were performed in 14 normal subjects with clinically patent arteries and 9 patients with calf claudication and arteri ographically confirmed peripheral vascular occlusion. The tests involved a stan dard exercise performed in the supine position. During rest periods the limb under test was subjected to simultaneous venous occlusion plethysmography.
In the patients with intermittent claudication, results were abnormal when compared with those of the normal group. The modified testing procedure de scribed gave discriminatory results for each group. Their usefulness in mon itoring disease progression, treatment benefit, and patient selection for surgery is discussed.
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