Weidmann, S. : The effect of the cardiac membrane potential on the rapid availability of the sodium carrying system. J. Physiol.Lond., 127: 213-224, 1955.
Zipes, D.P. , Fischer, J.C.: Effects of agents which inhibit the slow channel on sinus node automaticity and atrioventricular conduction in the dog. Circ. Res., 34: 184-1961974.
16.
Noble, D.: The Initiation of the Heart Beat. Oxford, Clarendon Press, 1975.
17.
Surawicz, B. : Calcium responses ("calcium spikes"). Am. J. Cardiol., 33: 689-690, 1974.
18.
Wellens, H.J.J. : Contribution of cardiac pacing to our understanding of the Wolff- Parkinson-White syndrome. Br. Heart J., 37: 231-241, 1975.
19.
Jewitt, D.E. , Singh, B.N.: The role of beta-adrenergic blockade in myocardial infarction. Prog. Cardiovasc. Dis., 16: 421-438, 1974.
20.
Han, J., Moe, G.K.: Non-uniform recovery of excitability in ventricular muscle. Circ. Res., 14: 44-50, 1964.
Vaughan Williams, E.M.: Electrophysiological aspects of the action of antiarrhythmic drugs. Proc. R. Soc. Med., 62: 75-77, 1969.
23.
Bigger, J.T., Jr., Mandel, W.J.: Effect of lidocaine on conduction in canine Purkinje fibers and at the ventricular muscle-Purkinje fiber junction. J. Pharmacol. Exp. Ther., 174: 487-499, 1970.
24.
Singh, B.N., Vaughan Williams, E.M.: Effect of altering potassium concentration on the action of lidocaine and diphenylhydantoin on rabbit and ventricular muscle. Circ. Res., 29: 286-297, 1971.
25.
Rosen, M.R. , Gelband, H., Hoffman, B.F.: Effects of blood perfusion on electrophysiological properties of isolated canine Purkinje fibres. Circ. Res. , 30: 575- 582, 1972 .
26.
Rosen, M.R. , Merker, C., Pippenger, C.E.: The effects of lidocaine on the canine ECG and electrophysiological properties of Purkinje fibers. Am. Heart J., 91: 191-202, 1976.
27.
Rosen, M.R. , Danilo, P., Alonso, M.B., et al.: Effects of therapeutic concentrations of diphenyldantoin on transmembrane potentials of normal and depressed Purkinje fibers. J. Pharmacol. Exp. Ther.197: 594- 604, 1976.
28.
Freedberg, A.S., Papp, J.G., Vaughan Williams , E.M.: The effect of altered thyroid state on atrial intracellular potentials. J. Physiol. , 207: 357-363, 1970.
29.
Singh, B.N. , Vaughan Williams , E.M.: The effect of amiodarone, a new anti-anginal drug, on cardiac muscle. Br. J. Pharmacol. , 39: 657-668, 1970.
30.
Vastesaeger, M., Gillot, P., Rasson, G.: Etude clinique d'une nouvelle medication anti-angoreuse. Acta Cardiol., 22: 483-490, 1967.
31.
Rosenbaum, M.B., Chiale, P.A., Ryba, D., et al.: Control of tachyarrhythmias associated with Wolff-Parkinson-White syndrome by amiodarone hydrochloride. Am. J. Cardiol., 34: 215-222, 1974.
32.
Cranefield, P.F., Aronson, R.S., Wit, A.L.: Effect of verapamil on the normal action potential and on a calcium-dependent slow response of canine cardiac Purkinje fibers. Circ. Res., 34: 204-213, 1974.
33.
Singh, B.N. , Vaughan Williams , E.M.: A fourth class of antidysrhythmic action? Effect of verapamil on ouabain toxicity, on atrial and ventricular intracellular potentials and on other features of cardiac function. Cardiovasc. Res., 6: 109-114, 1972.
34.
Heng, M.K., Singh, B.N., Roche, A.H.G., et al.: Effects of intravenous verapamil on cardiac arrhythmias and on the electrocardiogram. Am. Heart J., 90: 487- 498, 1975.
35.
Singh, B.N. : Antiarrhythmic effects of local anesthetics and calcium antagonists. Pharmacol. Ther., 2: 125-150, 1977.
36.
Singh, B.N. , Ellrodt, G., Peter, C.T.: The pharmacological effects and therapeutic applications of verapamil. Drugs (in press).
37.
Vaughan Williams, E.M.: The mode of action of quinidine on isolated rabbit atria interpreted from intracellular records. Br. J. Pharmacol., 13: 276-287, 1958.
38.
Watanabe, Y. , Dreifus, L.S.: Interactions of quinidine and potassium on atrioventricular transmission. Circ. Res., 20: 434-446, 1967.
39.
Conn, H.L.: Some considerations of quinidine and procainamide action at the cellular level . In The Myocardial Cell. Edited by S. A. Briller, H. L.Conn. Philadelphia, University of Pennsylvania Press, 1966, pp. 269-296.
40.
Heissenbuttel, R.H., Bigger, J.T.: The effect of oral quinidine on intraventricular conduction in man: Correlation of plasma quinidine with changes in QRS duration . Am. Heart J., 80: 453-462, 1970.
41.
Krikler, D.M. , Curry, P.V.L.: Torsade de pointes, an atypical ventricular tachycardia. Br. Heart J., 38: 117-120, 1976.
42.
Selzer, A., Wray, H.W.: Quinidine syncope: Paroxysmal ventricular fibrillation occurring during treatment of chronic atrial fibrillation. Circulation, 30: 17-26, 1964.
43.
Conn, H.L., Luchi, R.J.: Some cellular and metabolic considerations relating to the action of quinidine as a prototype antiarrhythmic agent. Am. J. Med., 37: 685- 699, 1964.
44.
Greenblatt, J.D., Wu, E.: Pharmacokinetic studies with short and long acting quinidine preparations. Angiology (in press).
45.
Kessler, K.M. , Lowenthal, D.T., Warner, H.: Quinidine elimination in patients with congestive heart failure or poor renal function. N. Engl. J. Med., 290: 706-709, 1974.
46.
Byrne-Quinn, E., Wing, A.J.: Maintenance of sinus rhythm after DC reversion of atrial fibrillation. Br. Heart J., 32: 370-376, 1970.
Lown, B., Wolf, M.: Approaches to sudden death from coronary heart disease. Circulation , 44: 130-142, 1970.
49.
Fors, W.J., VanderArk, C. R., Reynolds, E. W.: Evaluation of propranolol and quinidine in the treatment of quinidine-resistant arrhythmias. Am. J. Cardiol., 27: 190-194, 1971.
50.
Torok, E., Bajkay, G., Gulyas, A., et al.:Comparative study of a long acting quinidine preparation and quinidine sulphate in chronic and fibrillation. Pharmacol. Clin.2: 90-93, 1970.
Josephson, M.E., Caracta, A.R., Ricciutti, M.A., et al.: Electrophysiologic properties of procainamide in man. Am. J. Cardiol., 33: 596-603, 1974.
53.
Helfant, R.H. , Scherlag, B.J., Damato, A.N.: The electrophysiological properties of diphenylhydantoin sodium as compared to procainamide in the normal and digitalis-intoxicated dog. Circulation, 36: 108-118, 1967.
54.
Helfant, R.H. , Scherlag, B.J., Damato, A.N.: Use of diphenyldantoin sodium to dissociate the effects of procainamide on automaticity and conduction in the normal and arrhythmic heart. Am. J. Cardiol., 20: 820-825, 1967.
55.
Koch-Wester, J.: Pharmacokinetics of procainamide in man. Ann. N. Y. Acad. Sci., 179: 370-382, 1971.
56.
Giardina, E.G.V. , Heissenbuttel, R.H., Bigger, J.T.: Intermittent intravenous procainamide to treat ventricular arrhythmias. Ann. Intern. Med., 78: 183-193, 1973.
Singh, B.N. : Side effects of antiarrhythmic drugs. Pharmacol. Ther., 2: 151-166, 1977.
59.
Dubois, E.L. : Procainamide induction of a systemic lupus erythematosus syndrome. Presentation of six cases, review of the literature and analysis and follow up of reported cases. Medicine, 48: 217-228, 1969.
60.
Jewitt, D.E. , Kishon, Y., Thomas, M.: Lignocaine in the management of arrhythmias after acute myocardial infarction. Lancet, 1: 266-270, 1968.
61.
Gianelly, R. , Von der Groeben, J.O., Spivack, D., et al.: Effect of lidocaine on ventricular arrhythmias in patients with coronary heart disease. N. Engl. J. Med.,277: 1215-1219, 1967.
62.
Strong, J.M. , Parker, M., Atkinson, A.J., Jr.: Identification of glycinexylidide in patients treated with intravenous lidocaine. Clin. Pharmacol. Exp. Ther., 14: 67-72, 1973.
63.
Stenson, R.E. , Constantino, R.T., Harrison, D.C.: Interrelationships of hepatic blood flow, cardiac output and blood levels of lidocaine in man. Circulation , 41: 205-211, 1971.
Moe, G.K., Mendez, C.: The physiological basis of reciprocal rhythm. Prog. Cardiovasc. Dis., 8: 461-482, 1966.
66.
Thompson, P.D. , Rowland, M., Melmon, K.L.: The influence of heart failure, liver disease and renal failure on the disposition of lidocaine in man. Am. Heart J., 82: 417-421, 1971.
67.
Rosen, K., Lau, S.H., Weiss, M., et al.: The effect of lidocaine on atrioventricular and intraventricular conduction in man. Am. J. Cardiol., 25: 1-5, 1971.
68.
Lichstein, E., Chudda, K.D., Gupta, P.K.: Atrioventricular block with lidocaine therapy . Am. J. Cardiol., 31: 277-281, 1973.
Strauss, H.C. , Bigger, J.T., Basset, A.L., et al.: Actions of diphenylhydantoin on the electrical properties of isolated rabbit and canine atria. Circ. Res., 23: 463-477, 1968.
71.
Bigger, J.T. , Schmidt, D.H., Kutt, H.: Relationship between plasma level of diphenylhydantoin and its cardiac antiarrhythmic effects. Circulation, 38: 363-374, 1968.
72.
Rosen, M.R. , Liasak, R., Rubin, I.L.: Diphenylhydantoin in cardiac arrhythmias . Am. J. Cardiol., 20: 674-680, 1967.
73.
Ward, M., Mather, J.A.: Diphenylhydantoin intoxication mimicking botulism. N. Engl. J. Med., 286: 88-90, 1971.
Befeler, B. , Castellanos, A., Wells, D.E., et al.: Electrophysiological effects of the antiarrhythmic agent disopyramide phosphate. Am. J. Cardiol. , 35: 282-287, 1974.
76.
Singh, B.N.: Unpublished observations, 1977.
77.
Marriott, P.K. , Ruttley, M.S.T., Winterbottam , J.T., et al.: A study of the acute electrophysiological and cardiovascular action of disopyramide in man. Europ. J. Cardiol., 4: 303-312, 1976.
78.
Jensen, G., Sigurd, B., Uhrenhott, A.: Hemodynamic effects of intravenous disopyramide in heart failure. Eur. J. Clin. Pharmacol., 8: 167-173, 1975.
79.
Conway, J.F. , Bottomley, K., Wakely, E.J., et al.: Disopyramide in cardiac arrhythmias—An initial appraisal. J. Int. Med. Res., 1: 105-114, 1973.
80.
Vismara, L.A. , Mason, D.T., Amsterdam, E.A.: Disopyramide phosphate: Clinical efficacy of a new oral antiarrhythmic drug. Ther., Pharmacol. Exp. Ther., 16: 330-335, 1974.
81.
Jennings, G. , Model, D.G., Jones, M.B.S., et al.: Oral disopyramide in prophylaxis of arrhythmias following myocardial infarction. Lancet, 1: 51-54, 1976.
82.
Zainal, N., Carmichael, D.J.S., Griffiths, J.W., et al.: Oral disopyramide for the prevention of arrhythmias in patients with acute myocardial infarction admitted to open wards. Lancet, 2: 887-889, 1977.
83.
Spurrell, R.A.J. , Thorburn, C.W., Camm, J., et al.: Effects of disopyramide on electrophysiological properties of specialized conduction system in man and on accessory atrioventricular pathway in WPW syndrome. Br. Heart J., 37: 861-867, 1975.
84.
Karim, A.: The pharmacokinetics of norpace. Angiology, 26: 85-95, 1975.
85.
Conolly, M.E. , Kersting, F., Dollery, C.T.: The clinical pharmacology of beta- adrenoceptor-blocking drugs. Prog. Cardiovasc. Dis., 19: 203-234, 1977.