Panel Discussion Following the Survey By Dr. Berenson

Abstract

Get full access to this article

View all access options for this article.

References

Böttcher, C.J.F. , and Klynstra, F.B. : Mucopolysaccharides and atherosclerosis . Lancet, i: 167, 1965.

Klynstra, F.B. , Böttcher, C.J.F. , Van Melsen , J.A. and Van Der Laan, E.J. : Distribution and composition of acid mucopolysaccharides in normal and atherosclerotic human aortas. J. Atheroscler. Res., 7: 301, 1967.

Klynstra, F.B. , Boelsma-Van Houte , E. , and Böttcher, C.J.F. : Acid mucopolysaccharides and atherosclerosis. Lancet, ii: 1150, 1967 .

Laurent, T.C. , and Persson, H. : The interaction between polysaccharides and other molecules VII: The effect of various polymers on the sedimentation rate of serum albumin and α-crystallin. Biochim. Biophys. Acta , 83: 141, 1964.

Beneke, G. : Altersabhängige Veränderungen des Kollagen und der Bindegewebszellen. Altern und Entwicklung. Bd.2. Schriftenreihe der Mainzer Akademie . Stuttgart-New York : F. K. Schatteur 1971.

Berenson, G.S. : Distribution of acid mucopolysaccharides in inner and outer layers of bovine aorta. Circ. Res. 7: 889 (1959).

Berenson, G.S. , E.R. Dalferes Jr. , R. Robin and J.P. Strong : Mucopolysaccharides and atherosclerosis. In: R. J. Jones : Evolution of the atherosclerotic plaques. P. 139. Chicago: University of Chicago Press 1963.

Berenson, G.S. , and B. Radhakrishnamurthy : The role of connective tissue in cardiovascular disease. In: A. N. Brest and J. H. Moyen: Cardiovascular Disorders . Philadelphia: F. A. Davis Co. 1968.

Bertelsen, S. : Alterations in human aorta and pulmonary artery with age. Acta Path. Microbiol. Scand. 51: 206 (1961).

10.

Bertelsen, S. : Hexosamine, hydroxyproline and calcium levels in the intima of the human aorta as related to age and atherosclerotic changes . J. Geront. 17: 24 (1962).

11.

Boas, N. : Method for the determination of hexosamines in tissues. J. Biol. Chem. 204: 553 (1953).

12.

Böttcher, C.J.F. , and F.G. Klynstra : Content of acid mucopolysaccharides in the human aorta. J. Atheroscler. Res. 2: 263 (1962).

13.

Böttcher, C.J.F. , and F.B. Klynstra : Acid mucopolysaccharides in human aortic tissue. Their distribution at different stages of atherosclerosis . Lancet 2: 439 (1963).

14.

Boucek, R.J. , N.L. Noble , K. Kao and H.R. Eldern : The effects of age, sex and race upon the acetic acid fractions of collagen. J. Geront. 13: 2 ( 1958).

15.

Buddecke, E. : Angiochemische Alterswandlungen des Aortenbindegewebes . Dtsch. Ges. Kreisl.-Forsch. 24: 143 (1958).

16.

Buddecke, E. : Biochemie des Bindegewebes. Angew. Chemie 72: 663 (1960a).

17.

Buddecke, E. : Untersuchungen zur Chemie der Arterienwand. V. Darstellung und chemische Zusammensetzung von Mucopolysacchariden der Aorta des Menschen. Hoppe Seyler's Z. Physiol. Chem. 318: 33 (1960b).

18.

Buddecke, E. : Die Mucopolysaccharide der Gerfäßwand. Dtsch. med. Wschr. 86: 1773 (1961).

19.

Clausen, B. : Influence of age on connective tissue. Hexosamine and hydroxyproline in human aorta, myocardium and skin. Lab. Invest. 11: 229 (1962a).

20.

Clausen, B. : Influence of age on connective tissue. Uronic acid and uronic acid-hydroxyproline ratio in human aorta, myocardium and skin . Lab. Invest. 11: 1340 (1962b).

21.

Clausen, B. : Influence of age on connective tissue. Lab. Invest. 11: 229 (1963).

22.

Curran, R.C. , and W.A.J. Crane : Mucopolysaccharides in the atheromatous aorta J. Path. Bact. 84: 405 (1962).

23.

Dyrby, M.P. : Studies on the metabolism of mucopolysaccharides of human arterial tissue by means of 35S with special reference of changes related to age. J. Geront. 14: 32 (1959).

24.

Gerlach, U. : Über die Altersabhängigkeit der Aktivitat sulfataktivierender Enzyme im Herzen . Klin. Wschr. 41: 873 (1963).

25.

Gries, G. : Biochemische Untersuchungen über die Physiologie, Pathophysiologie und therapeutische Beeinflussung des Stoffwechselsvon Kollagen im Rahmen des Bindegewebsstoffwechsels . Habil.-Schrift, Berlin 1965.

26.

Gore, I. , Y. Tanaka and E. Kimoto : Changes in the acid mucopolysaccharides of human aortae with age and atherosclerosis . Circulation Res. 30: 10 (1964).

27.

Hauss, W.H. , G. Junge-Hülsing and H.J. Holländer : Changes in metabolism of connective tissue associated with ageing and arterio-atherosclerosis . J. Atheroscler. Res. 2: 50 ( 1962).

28.

Hauss, W.H. : Die Rolle der Mesenchymzellen in der Pathogenese der Arteriosklerose . Doc. Angiologorum II: 11-39 (1970).

29.

Haust, M.D. , and R.H. More : Morphological evidence of different mode of "secretion" of connective tissue precursors by fibroblasts and by smooth 'muscle cells. An electron microscopic study. Am. J. Path. 48: 15 a (1966).

30.

Haust, M.D. , and R.H. More : Electron microscopy of connective tissue and elastogenesis. In: B. M. Wagner and D. E. Smith: The Connective Tissue. Baltimore : The Williams & Wilkins Co. 1967.

31.

Helin, P. , I. Lorenzen , C. Garbarsch and M.E. Matthiessen : Arteriosclerosis and hypoxia. Part 2. Biochemical changes in mucopolysaccharides and collagen of rabbit aorta induced by systemic hypoxia. J. Atheroscler. Res. 9: 295 (1969).

32.

Hilz, H. : Neue Erkenntnisse zur Biochemie und Klinik des Bindegewebsstoffwechsels . Habil.-Schrift

Hamburg

1960.

33.

Hilz, H. , and D. Uermann : Der Sulfatstoffwechsel der Gefäßwand in Beziehung zur Arteriosklerose und seine Beeinflussung durch Sexualhormone. Biochem. Z. 332: 376 (1960).

34.

Hilz, H. , C. Erich und D. Glaubitt : Veränderungen von Zelldichte und Polysaccharidstoffwechsel im alternden Bindegewebe . Klin. Wschr. 41: 332 (1963).

35.

Junge-Hülsing, G. : Untersuchungen zur Pathophysiologie des Bindegewebes . Habil.-Schrift

Münster

1963, Bd. 24, Theoret. und Klin. Med. in Einzeldarstellungen. Heidelberg: Hüthig 1965.

36.

Kao, K.T. , D.M. Hilker and T.H. McGavack : Connective tissue. V. Comparison of synthesis and turnover of collagen and elastin in tissues of rat at several ages. Proc. Soc. Exp. Biol. Med. 106: 335 (1961).

37.

Kaplan, D. , and K. Meyer : Mucopolysaccharides of aorta at various ages. Proc. Soc. Exp. Biol. Med. 105: 78 (1960).

38.

Kirk, J.E. , and M. Dyrbye : Mucopolysaccharides of human arterial tissue. II. Analysis of total isolated mucopolysaccharide material. J. Gerontol. 12: 23 (1957).

39.

Kirk, J.E. : Mucopolysaccharides of arterial tissue. In: A. I. Lansing : The Arterial Wall, Aging, Sructure and Chemistry. Baltimore: The Williams & Wilkins Co. 1959.

40.

Klynstra, F.B. , C.J.F. Böttcher , J.A. Van Melsen and E.J. Van der Laan : Distribution and composition of acid mucopolysaccharides in normal and atherosclerotic human aortas. J. Atheroscler. Res. 7: 301 (1967).

41.

Kumar, V. , G.S. Berenson , H. Ruiz , E.R. Dalferes , Jr., and J.P. Strong : Acid mucopolysaccharides of human aorta. Part I. Variations with maturation. J. Atheroscler. Res. 7, 573 (1967a)

42.

Kumar, V. , G.S. Berenson , H. Ruiz , E.R. Dalferes , Jr., and J.P. Strong : Acid mucopolysaccharides of human aorta. Part 2. Variations with atherosclerotic involvement. J. Atheroscler. Res. 7: 583 (1967b).

43.

Levene, G.I. , and J.C.F. Poole : The collagen content of the normal and atherosclerotic human aortic intima. Brit. J. Exp. Path. 43: 469 (1962).

44.

Likar, L.J. , I.N. Likar and R.W. Robinson : Levels of acid mucopolysaccharides of the bovine aorta at different stages of the sexual cycle. J. Atheroscler. Res. 5: 388 (1965).

45.

Lindner, J. , G. Gries , G. Freytag und J. Kind : Stoffwechseluntersuchungen an der atherosklerotischen Gefäßwand. Verh. Dtsch. Ges. Path. 51: 228 (1967).

46.

Lindner, J. : The histochemistry of atherosclerosis. In: F. H. Schettler and G. S. Boyd : Atherosclerosis, p. 73-140. Amsterdam: Elsevier 1969.

47.

Lindner, J. : Veränderungen der Gesamtgefäßwand: In: R. Marx u.H. A. Thies : Alter und Blutgerinnung. S. 27. New York-Stuttgart 1970.

48.

Lindner, J. : Histochemie der Arterienwand. In: G. Heberer , G. Rau und. W. Schoop : Angiologie, 2. Auflage. Stuttgart : Thieme 1971a (im Druck).

49.

Lindner, J. : "Bindegewebe": In: G. Holle: "Altern": Band VI/4, Handbuch der Allgemeinen Pathologie. Berlin- Heidelberg-New York: Springer 1971b (im Druck).

50.

Lindner, J. , and K. Grasedyck : Determination of tissue collagen peptidases attacking apolar peptide sequences. Z. Klin. Chem. u. Klin. Biochem. 9: 68 (1971c).

51.

Lorenzen, I. : Alterations in acid mucopolysaccharides and collagen of rabbit aorta related to age of epinephrine-thyroxine induced arteriosclerotic lesions. Acta Endocrinol. 39: 615 (1962).

52.

Lowry, O.H. , D.R. Gilligan and E.M. Katersky : Determination of collagen and elastin in tissues, with results obtained in various normal tissues from different species. J. Biol. Chem. 139: 795 (1941).

53.

McGavack, T.H. , and K.T. Kao : The influence of age and sex on the soluble collagen, insoluble collagen and elastin of rat tissues. Exp. Med. Surg. 18: 104 (1960).

54.

McGavack, T.H. , and K.T. Kao : Aging in connective tissue. A dynamic process . J. Amer. Geriatric Soc. 11: 1024 (1963 ).

55.

Milch, R.A. , J.R. Jude and J. Knaack : Effects of collagen reactive aldehyde metabolism on the structure of the canin aortic wall and their possible role in atherogenesis. Surgery 54: 104 (1963).

56.

Nakamura, T. , K. Tokita , S. Tateno , T. Kotoku and T. Ohba : Human aortic acid mucopolysaccharides and glycoproteins. Changes during aging and in atherosclerosis. J. Atheroscler. Res. 8: 891 (1968).

57.

Neumann, R.E. , and M.A.J. Logan : The determination of collagen and elastin in tissues. Biol. Chem. 186: 549-556 (1950).

58.

Platt, D. , and H.P. Luboeinski : Der katabole Mucopolysaccharid-stoffwechsel der menschilichen Aortenwand in Abhängigkeit vom Alter. J. Geront. 2: 17 (1969).

59.

Platt, D. : Altersabhangige Aktivitätsänderungen lysosomaler Enzyme (Glykosaminoglykan-Hydrolasen) in Serum und Organen des Menschen. Dtsch. med. Wschr. 95: 634 (1970).

60.

Platt, D. : Biochemische Aspekte zum Altern der Interzellularsubstanz. actuelle Geron. 1: 81 (1971).

61.

Schorah, C.J. , D. Lovell and R.C. Curran : Arterial acid mucopolysaccharide concentrations: The correlation with age and intimal hyperplasia. Brit. J. Exp. Path. 49: 574 (1968).

62.

Smith, E.B. : The influence of age and atherosclerosis on the chemistry of aortic intima. Part 2. Collagen and mucopolysaccharides. J. Atheroscler. Res. 5: 241 (1965).

63.

Souadjian, J.V. , B.A. Kottke and J.L. Titus : Acid mucopolysaccharides of aorta. Relationship to atherosclerosis. Arch. Path. 87: 586 (1969).

64.

Wahl, P. : Angiochemie der Arteriosklerose. Z. Alternsforsch. 16: 304 (1963).

65.

Wissler, R.W. : Arterial media cell, smooth muscle or multifunctional mesenchym cell. J. Atheroscler. Res. 8: 201 (1968).

66.

Zugibe, F.T. : Relationship between the chondroitin sulphates and collagen in human arteries with aging. J. Geront. 16: 392 (1961).