Coronary Heart Disease: Reduction of Death Rate By Chondroitin Sulfate a

Morrison, L.M. , Murata, K. , Quilligan, J.J. , Jr., Schjeide , O.A. and Freeman. L. : Prevention of atherosclerosis in sub-human primates by chondroitin sulfate A, Circulation Research 19: 358, 1966.

Morrison, L.M. , Bernick, S. , Alfin-Slater, R.B. , Patek, P.R. and Ershoff, B.H. : Inhibition of coronary atherosclerosis in the x-irradiated, cholesterol-fed rat by chondroitin sulfate A, Proc. Soc. Exp. Biol. & Med. 123: 904, 1966.

Kurita, H. : Uber den Einfluss des chondroitin-sulfates auf die experimentelle atherosklerose in kaninchen, Med. J. Shinshu University 1: 23, 1955.

Ohdoi, S. : A supplementary study of sulfated mucopolysaccharides and experimental atherosclerosis , Tokyo J. Med. Sc. 67: 1291, 1959.

Murata, K. : Inhibitory effects of chondroitin polysulfate on lipemia and atherosclerosis in connection with its anticoagulant activity, Naturwissenschaften 49: 1, 1962.

Oshima, Y. Yokohari, R. , Ohdoi, T. , Murata, K. , Wago, K. , Otsuki, A. , Noda. M. and Miyamoto, T. : Clinical and experimental studies on mucopolysaccharides (Mucopolysaccharide and atherosclerosis) in Biochemistry and Medicine of Mucopolysaccharides. Ed. Egami F. and Oshima, Y. p. 259, 1962.

Morrison, L.M. , Quilligan, J.J. , Jr., Murata, K. , Schjeide, O.A. , Freeman, L. and Ershoff, B.H. : Treatment of atherosclerosis with acid mucopolysaccharides, Exp. Med. Surg. 25#1: 61, 1967 .

Morrison, L.M. , Rucker, P.G. and Ershoff, B.H. : Prolongation of thrombus-formation in rabbits given chondroitin sulfate A, J. Athero. Res. 8: 319, 1968.

Morrison, L.M. : Treatment of coronary arteriosclerotic heart disease with chondroitin sulfate A: Preliminary report, J. Amer. Geriatrics Soc. 16#7: 779, 1968.

Robbins, R.C. , Morrison, L.M. and Simpson, C.F. : Effect of chondroitin sulfate A and flavonoids on hypervitaminosis D in rats, Proc. Soc. Exp. Biol. & Med. 131#3: 719, 1969.

Morrison, L.M. , Branwood, A.W. , Ershoff, B.H. , Murata, K. , Quilligan, J.J. , Jr., Schjeide , O.A. , Patek, P.R. , Bernick, S. , Freeman, L. , Dunn, O.J. and Rucker, P.G. : The prevention of coronary arteriosclerotic heart disease with chondroitin sulfate A: preliminary report, Exp. Med. Surg. 27#3: 278, 1969.

Morrison, L.M. , Bajwa, G.S. and Ershoff, B.H. : Prolongation of plasma thrombus formation time of dogs administered chondroitin sulfate A and C, Exp. Med. Surg. 28: 188. 1970.

Morrison, L.M. : Reduction of ischemic coronary heart disease by chondroitin sulfate A, Angiology 22#3: 165, 1971.

Morrison, L.M. , Bajwa, G.S. , Alfin-Slater , R.B. and Ershoff, B.H. : Prevention of vascular lesions by chondroitin sulfate A in the coronary artery and aorta of rats induced by a hypervitaminosis D, cholesterol-containing diet, Atherosclerosis . In press.

Morrison, L.M. : Cholesterol metabolism: blood serum cholesterol and ester levels in 200 cases of acute coronary thrombosis. Amer. J. Med. Sci. 216: 32, 1948.

Holman, R.L. , McGill, H.C. , Jr., Strong, J.P. , and Geer, J.C. : The natural history of atherosclerosis. The early aortic lesions seen in New Orleans in the middle of the 20th century . Am. J. Path. 34: 209,1958.

Morrison, L.M. , Schjeide, O.A. , Quilligan, J.J. , Freeman, L. and Murata, K. : Metabolic Parameters of the growth-stimulating effect of chondroitin sulfate A in tissue cultures, Proc. Soc. Exp. Biol. & Med. kk9: 618, 1965.

Chandler, A.B. : In vitro thrombotic coagulation of the blood. A method for producing a thrombus. Lab. Invest. 7: 110, 1958.

Morrison, L.M. and Schjeide, O.A. : Coronary heart disease and the acid mucopolysaccharides (glvcosaminoglycans). Charles C. Thomas, Publisher. In press.

Murata, K., Quilligan, J. J., Jr., Morrison, L. M. and Schjeide, O. A.: Unpublished data.

Morrison, L.M. , Rucker, P.G. and Dunn, O.J. : Prolongation of thrombus formation time in angina pectoris by chondroitin sulfate A. Abstract. Circulation Supple. II, 35 & 36: 28, 1967.

Srinivasan, S. and Sawyer, P.N. : The effect of thrombogenic and antithrombogenic drugs on the surface charge characteristics of the blood vessel wall and blood cells, Federation Proc. 27: 322, 1968.

Schiller, S. : The isolation of chondroitin sulfuric acid from normal human plasma, Biochem. Biophys. Acta 28: 423, 1958.

Meyer, K. : Biochemistry and biology of mucopolysaccharides. Amer. Jour. of Med. 47 #5: 664, Nov. 1969.

Kirk, J.E. and Dyrbye, M. : Mucopolysacchardies of human arterial tissue II. Analysis of total isolated mucopolysaccharide material. J. Gerontology 12: 23, 1957.

b. Berenson, G.S. , Dalferes, E.R. , Robin, R. and Strong, J.P. : Mucopolysaccharides and atherosclerosis. In: Evolution of the Atherosclerotic Plaque. R. J. Jones , ed., Chicago Press, p. 144, 1963.

Morrison, L.M. : Reduction of Mortality Rate in Coronary Thrombosis by Low-Cholesterol, Low-Fat Diet. Amer. Heart J. 42: 638, 1951.

Morrison, L.M. : A Nutritional Program For Prolongation of Life in Coronary Atherosclerosis. J.A.M.A. 159: 1425, 1955 .

Morrison, L.M. : Diet in Coronary Atherosclerosis. J.A.M.A. 173: 884, 1960.