A Fine Structure Study of Injury to the Endothelial Cells of the Rabbit Abdominal Aorta by Various Stimuli

Anitschkow, N. : In E. V. Cowdry's Arteriosclerosis: a survey of the problem, p. 272. Macmillan Co., New York. 1933.

Alksne, J.F. : The passage of colloidal particles across the dermal capillary wall under the influence of histamine. Quart. J. Exp. Physiol., 44: 51, 1959.

Baumgartner, H.R. , and Studer, A. : Gezielte Uberdehnung der Aorta abdominalis am normo- und hypercholesterinaemischen Kaninchen. Path. et Microbiol. (Basel), 26: 129, 1963.

Bessis, M. : Cell agony and death in cellular injury. Ciba Foundation Symposium , 287, 1964.

Buck, R.C. : The fine structure of endothelium of large arteries. J. Biophys. Biochem. Cytol., 4: 187, 1958.

Buck, R.C. : Intimal thickening after ligature of arteries; an electron-microscopic study . Circ. Res., 9: 418, 1962.

Buckley, I.K. : Cellular Injury in vitro: phase contrast studies on injured cytoplasm. J. Cell Biology, 14: 4/1, 1962.

Burch, G.E. , and de Pasquale, N.P. : Bradykinin. Am. J. Heart, 65: 116, 1963.

Cotran, R.S. , La Gattuta, M. , and Majno, G. : Studies on inflammation. Fate of intramural vascular deposits induced by histamines . Amer. J. Path., 47: 1045, 1965.

Courtice, F.C. and Schmidt-Diedrichs , A. : Lipid deposition in the injured wall of the carotid artery in the hypercholesterolemic and hyperlipemic rabbit. Quart. J. Exp. Physiol., 47: 228, 1962.

Cox, G.F. , Trueheart, R.E. , Kaplan, J. , and Taylor, C.B. : Atherosclerosis in rhesus monkeys. Repair of arterial injury—an important secondary atherogenic factor. Arch. Path., 76: 166, 1963.

French, J.F. , Jennings, M.A. , and Florey, H.W. : Morphological studies on atherosclerosis in swine. Ann. N. Y. Acad. Sci., 127: 798, 1965.

Friederici, H.H.R. : Extrusion of basal endothelial projections through the capillary basement membrane. Angiology, 16: 163, 1965.

Friedman, M. , and Byers, S.O. : Aortic atherosclerosis intensification in rabbits by prior endothelial denudation . Arch. Path., 79: 345, 1965.

Gottlob, R. : Experimental investigations on the local injuries caused by contrast media in aortography. Minerva cardionagiol. europea, 5: 83, 1957.

Gottlob, R. , and Zinner, G. : Uber die Schädigung des Venenendothels durch verschiedene Noxen. Wr. klin. Wschr., 71: 482, 1959.

Gottlob, R. , and Zinner, G. Uber die Regeneration geschädigter Endothelien nach hartem und weichem Trauma. Virchow's Arch. path. Anat., 336: 16, 1962.

Hackensellner, H.A. , and David, H. Vergleichende elektronenmikroskopische Untersuchungen am Endothel grosser Gefässe. Frankfurt Z. Path., 71: 194, 1961.

Hackensellner, H.A. , David, H. , and Uerlings, I. Licht- und elektronenmikroskopische Untersuchungen an doppelt liegierten Arterien (A. carotis des Kanninchens). Acta biol. med. german., 14: 34, 1965.

Hess, R. , and Stäubli, W. The development of aortic lipidosis in the rat, a correlative histochemical and electron microscopic study. Am. J. Path., 43: 301, 1963.

Hills, C.P. Ultrastructural changes in the capillary bed of the rat cerebral cortex in anoxic-ischaemic brain lesions. Am. J. Path., 44: 531, 1964.

Hoff, H.F. , McDonald, L. , and Hayes, T. An electron microscope study of the rabbit abdominal aortic intima after short-term ligation. To be published.

Jagannathan, S.N. , Madhavan, T.V. , and Goplan, C. Effects of adrenaline on aortic structure and serum cholesterol in Macaca Radiata. J. Atheroscl. Res. , 4: 335, 1964.

Kelly, F.B. , Jr., Taylor, C.B. , and Hass, G.M. : Localization of lipids in experimental arterial lesions of rabbits with hypercholesterolemia. Arch. Path., 53: 419, 1952.

Lewis, G.P. : Pharmacological actions of bradykinin and its role in physiological and pathological reactions. Ann. New York Acad. Sci., 104: 236, 1963.

Lorenzen, I. : Epinephrine induced alterations in connective tissue of aortic wall in rabbits. Proc. Soc. exp. Biol. Med. (N. Y.), 102: 440, 1959.

Luft, J.H. Improvements in epoxy resin embedding methods. J. Biophys. Biochem. Cytol., 9: 409, 1961.

Magarey, F.R. The effects of hypertension on the rat aorta . J. Path. Bact., 73: 121, 1957.

Majno, G. , and Palade, G.E. Studies on inflammation. I. The effects of histamine and serotonin on vascular permeability: an electron microscopic study. J. Biophys. Biochem. Cytol., 11: 571, 1961.

Manuelidis, E.E. Pathological swelling and vacuolization of cells . In Frontiers in cytology, Sanford L. Palay , editor, Yale Univ. Press, New Haven. 1958.

Marchesi, V.T. The passage of colloidal carbon through inflamed endothelium. Proc. Roy. Soc., 156: 550, 1962 .

Miles, A.A. Large molecular substances as mediators of the inflammatory response. Ann. New York Acad. Sci., 116: 855, 1964.

Miles, A.A. , and Wilhelm, D.L. The activation of endogenous substances inducing pathological increases of capillary permeability in the biochemical response to physical injury. In The biochemical response to physical injury, p. 51. Blackwell Scientific Publ., Oxford. 1960.

Movat, H.Z. , and Fernando, N.V.P. Acute inflammation. I. The earliest fine structural changes at the blood tissue barrier. Lab. Invest. , 12: 895, 1963.

Palade, G.E. : A study of fixation for electron microscopy . J. Exp. Med., 95: 285, 1952.

Parker, F. : An electron microscope study of coronary arteries. Amer. J. Anat., 103: 247, 1958.

Pease, D.C. , and Paul, W.J. : Electron microscopy of elastic arteries: the thoracic aorta of the rat. J. Ultrastruct. Res., 3: 469, 1960.

Reynolds, E.S. The use of lead citrate at high pH as an electron opaque stain in electron microscopy. J. Cell Biol., 17: 208, 1963.

Rocha e Silva, M. Chemical mediators of the acute inflammatory reaction. Ann. New York Acad. Sc., 105: 899, 1964 .

Rowley, D.A. Venous constriction as a cause of increased vascular permeability produced by 5-hydroxytryptamine, histamine, bradykinin and 48/80 in the rat. Brit. J. Exper. Path., 45: 56, 1964.

Sabatini, D.D. , Bensch, K. , and Barrnett, R.J. Cytochemistry and electron microscopy. The preservation of cellular ultrastructure and enzymatic activity by aldehyde fixation. J. Cell Biol., 17: 19, 1963.

Seifert, K. , and Hartmann, F. Die Feinstruktur der Schweine-aorta beim experimentellen Lathyrismus. Zschr. f. Zellforsch., 59: 878, 1963.

Shimamoto, T. Edematous reactions in arteries and atherosclerosis and thrombosis. J. Atheroscler. Res., 3: 87, 1963.

Shimamoto, T. , and Ishioka, T. Release of a thromboplastic substance from arterial walls by epinephrine. Circulation Res., 12: 138, 1963.

Sinapius, D. Zur Frage der blasigen Quellung des Gefässendothels in Suspensionslösungen (Potocytose im Sinne Zollingers). Zschr. f. Zellforsch., 44: 441, 1956.

Sinapius, D. Die frühen Leichenerscheinungen des Gefässendothels . Virchow's Arch. path. Anat., 331: 138, 1958 .

Spector, W.G. , and Willoughby, D.A. : The inflammatory response. Bact. Rev., 27: 117, 1963.

Ssolowjej, A. : Uber experimentelle hervorgerufene Elasticarisse der Arterien und deren Bedeutung für Lipoidablagerung. Virchow's Arch. f. path. Anat., 283: 213, 1932.

Stehbens, W.F. , and Silver, M.D. : Arterial lesions induced by methyl cellulose . J. Am. Path., 48: 483, 1963.

Steiner, J.W. , and Carruthers, J.S. Experimental extrahepatic biliary obstruction . Am. J. Path., 40: 253, 1962.

Still, W.J.S. An electron microscope study of cholesterol atherosclerosis in the rabbit. Exp. Mol. Path., 2: 491, 1963.

Taylor, C.B. , Cox, G.E. , Hall-Taylor, B.J. , and Nelson, L.G. Atherosclerosis in areas of vascular injury in monkeys with mild hypercholesterolemia. Circulation, 10: 613, 1954.

Tedder, E. , and Shorey, C.D. Intimal changes in venous stasis; an electron microscopic study. Lab. Invest., 14: 108, 1965.

Trump, B.F. , and Janigan, D.T. The pathogenesis of cytologic vacuolization in sucrose nephrosis. Lab. Invest., 11: 395, 1962.

Warren, S. Effects of radiation on normal tissues. VI. Effects of Radiation on Cardiovascular System. Arch. Path., 34: 1070, 1942.

Waters, L.L. Localization of lipids in injured coronary arteries of dogs following injections of egg-yolk fractions of hyperlipemic human plasma . Circulation, 8: 437, 1953.

Waters, L.L. The reaction of the artery wall to injury by chemicals or infection. Symposium on atherosclerosis. National Academy of Sciences, National Res. Council, 91, 1955.

Wells, F.R. , and Miles, A.A. Site of the vascular response to thermal injury. Nature, London, 200: 1015, 1963.

Wilhelm, D.L. The mediation of increased vascular permeability in inflammation. Pharmacol. Rev. 14: 251, 1962.

Williams, A.W. : Relation of atheroma to local trauma. J. Path. Bact., 81: 419, 1961.

Williams, A.W. , and Montgomery, G.L. : Chemical injury of arteries. J. Path. Bact., 77: 63, 1959.

Zollinger, H.U. : Cytologic studies with the phase microscope. I. The formation of blisters on cells in suspension (Protocytosis), with observations on the nature of the cellular membrane. Am. J. Path., 24: 545, 1948.